Results 111 to 120 of about 1,206,149 (284)

Clinicopathological and pedigree investigation of a novel spinocerebellar neurological disease in juvenile Quarter Horses in North America

open access: yesJournal of Veterinary Internal Medicine
Background In 2020, a novel neurologic disease was observed in juvenile Quarter Horses (QHs) in North America. It was unknown if this was an aberrant manifestation of another previously described neurological disorder in foals, such as equine neuroaxonal
Andrew T. Willis   +23 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calf skinfold measurements as a diagnostic tool for lipodystrophy syndromes: a cross-sectional study

open access: yesDiabetology & Metabolic Syndrome
Background Lipodystrophy syndromes (LS) are characterized by reduced body fat and associated metabolic complications, such as insulin resistance and diabetes. The diagnosis of LS can be challenging in clinical settings.
Grayce Ellen da Cruz Paiva Lima   +14 more
doaj   +1 more source

Testing for the Existence of Bargaining in Rural Households: a Study of Decisions on Labor Market Participation in the Cordillera Region of the Philippines [PDF]

open access: yes
In this paper we derive testable implications of a unitary farm household model and a non-unitary, i.e. bargaining, model. In the unitary household model the impact of spouse specific resources and non-labor income on household decisions should not be ...
Lodewijk Berlage   +1 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Brazilian expert consensus on the diagnosis, classification, screening for complications and treatment of familial partial lipodystrophy

open access: yesDiabetology & Metabolic Syndrome
Background Partial lipodystrophies are a rare and heterogeneous group of diseases characterized by variable loss of adipose tissue. Around the world, the high heterogeneity in phenotypic expression, limited awareness, and absence of standardized ...
Cynthia Melissa Valerio   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Anthropometric measurements as a key diagnostic tool for familial partial lipodystrophy in women

open access: yesDiabetology & Metabolic Syndrome
Background Familial Partial Lipodystrophy (FPLD) is a disease with wide clinical and genetic variation, with seven different subtypes described. Until genetic testing becomes feasible in clinical practice, non-invasive tools are used to evaluate body ...
Victor Rezende Veras   +10 more
doaj   +1 more source

New coherent states and modified heat equations

open access: yes, 2013
We clarify the relations between certain new coherent states for loop quantum gravity and the analytically continued heat kernel coherent states, highlighting the underlying general construction, the presence of a modified heat equation as well as the ...
Pittelli, Antonio, Sindoni, Lorenzo
core  

Inherited Cardiomyopathies

open access: yesNew England Journal of Medicine, 2011
Schwartz, Robert S.   +3 more
openaire   +3 more sources

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