Results 191 to 200 of about 48,210 (290)

Measuring Rod- and Cone-Photoreceptor-Specific Vision in Inherited Retinal Diseases Using a Commercial Perimeter. [PDF]

Invest Ophthalmol Vis Sci
Wu V, Roman AJ, Galsterer EL, Ansari G, Erdinest I, Righetti G, Viarbitskaya I, Russell RC, Kim RJ, Charlier J, Pfau K, Stingl K, Banin E, Pfau M, Stingl K, Aleman TS, Cideciyan AV.   +16 more
europepmc   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Gene therapy to treat inherited and complex retinal degenerative diseases

Molecular Therapy: Methods & Clinical Development, 2015
Tonia S Rex
doaj   +1 more source

Cystoid Macular Lesions in Inherited Retinal Diseases: Prevalence, Characteristics, and Genetic Associations in a Hungarian Cohort. [PDF]

Genes (Basel)
Asboth B, Sanrocco A, Besztercei B, Lesch B, Takacs A, Vamos R, Varsanyi B, Vegh A, Knezy K, Szabo V, Nagy ZZ, Zobor D.   +11 more
europepmc   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Assessing Agreement between Blue-Light and Green-Light Autofluorescence of Macular Hyperautofluorescent Rings in Inherited Retinal Diseases. [PDF]

Ophthalmol Sci
Daich Varela M, Aychoua N, Rashid M, Lopes A, Michaelides M.   +4 more
europepmc   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca, Gianmauro Palombelli, Nicola Vanacore, Rossella Canese   +3 more
wiley   +1 more source

Base and Prime Editing for Inherited Retinal Diseases: Delivery Platforms, Safety, Efficacy, and Translational Perspectives. [PDF]

Pharmaceutics
Zhang H, Li Y, Li J, Li X, Li T.
europepmc   +1 more source

Transparent White OLED‐Based Brain Stimulation With Invisible Flicker and Photobiological Safety Evaluation

Journal of the Society for Information Display, EarlyView.
A safe, transparent, invisible flickering transparent white OLED (TrWOLED) platform is developed for therapeutic 40 Hz brain stimulation. By utilizing chromatic modulation, this device delivers effective gamma frequency brain entrainment while eliminating visual fatigue.
Younghun Jung, Minwoo Park, Kyung Cheol Choi   +2 more
wiley   +1 more source

Stem cell-based therapies for inherited retinal diseases - Translational advances and clinical evidence: A review.

Biomol Biomed
Huang Y, Xie Y, Wang C.
europepmc   +1 more source