Results 11 to 20 of about 370,744 (189)
Cellular and Molecular Mechanisms of Pathogenesis Underlying Inherited Retinal Dystrophies
Biomolecules, 2023 Inherited retinal dystrophies (IRDs) are congenital retinal degenerative diseases that have various inheritance patterns, including dominant, recessive, X-linked, and mitochondrial.
Andrew Manley +3 more
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The landscape of basic gene therapy approaches in inherited retinal dystrophies [PDF]
Frontiers in Ophthalmology, 2023 The study of gene therapies has been of particular interest in recent decades due to their promising potential to slow or even rescue the degeneration of the retina in inherited retinal dystrophies (IRDs).
Jianhua Xia, Lei Gu, Qing Pan
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Molecular Therapy: Nucleic Acids, 2023 Inherited retinal dystrophies comprise a broad group of genetic eye diseases without effective treatment. Among them, Stargardt disease is the second most prevalent pathology.
Laura Siles +4 more
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Descriptive study of a cohort of 488 patients with inherited retinal dystrophies [PDF]
, 2021 Producción CientíficaABSTRACT. PURPOSE: To analyze the distribution of inherited retinal diseases (IRDs), describe the clinical characteristics of patients, and determine the percentages of patients with genetic diagnosis in the Castilla y Leon region of
Coco Martín, Rosa María +4 more
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Inherited Macular Dystrophies and Differential Diagnostics [PDF]
, 2012 The inherited macular dystrophies are characterized by different grade central visual loss and different character macula atrophy, because of retinal pigment epithelium lesion. The cause of photoreceptors degeneration is still not known. In this article,
Virginija Ašmonienė +5 more
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Updating the Genetic Landscape of Inherited Retinal Dystrophies
Frontiers in Cell and Developmental Biology, 2021 Inherited retinal dystrophies (IRD) are a group of diseases characterized by the loss or dysfunction of photoreceptors and a high genetic and clinical heterogeneity.
Belén García Bohórquez +13 more
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Gene therapy for inherited retinal dystrophies. [PDF]
, 2023 Inherited retinal dystrophies are a group of relatively rare genetic disorders that cause progressive degeneration of the retina, leading to vision loss, which causes lots of difficulties and challenges to patients in everyday life.
Kobeckis, Kamilis,
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Evidenzbasierte Diagnostik hereditärer Netzhautdystrophien 2009 = Evidence-Based Diagnostic Approach to Inherited Retinal Dystrophies 2009 [PDF]
, 2009 Background: Hereditary retinal dystrophies comprise a heterogeneous group of inherited retinal disorders with variable clinical presentation and multiple associated genes. Clinical diagnosis and differential diagnosis are difficult.
Weber, Bernhard H. F. +5 more
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Nature Communications, 2022 Retinal dystrophies such as Retinitis pigmentosa are among the most prevalent causes of inherited incurable legal blindness. Here the authors demonstrate that conjugated polymer nanoparticles reinstate visual functions in aged rats with fully degenerated
S. Francia +19 more
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Gene therapy for inherited retinal dystrophies [PDF]
, 2009 The inherited retinal dystrophies comprise a large number of disorders characterized by a slow and progressive retinal degeneration. They are the result of mutations in genes that express in either the photoreceptor cells or the retinal pigment ...
Côco, Monique [UNIFESP] +2 more
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