Results 51 to 60 of about 5,980 (178)

A Novel Time-Aware Deep Learning Model Predicting Myopia in Children and Adolescents

Ophthalmology Science
Objective: To quantitatively predict children’s and adolescents’ spherical equivalent (SE) by leveraging their variable-length historical vision records. Design: Retrospective analysis.
Ana Maria Varošanec, MD, Leon Marković, MD, Zdenko Sonicki, MD, PhD   +2 more
doaj   +1 more source

The Evolution of Fabrication Methods in Human Retina Regeneration

Applied Sciences, 2021
Optic nerve and retinal diseases such as age-related macular degeneration and inherited retinal dystrophies (IRDs) often cause permanent sight loss. Currently, a limited number of retinal diseases can be treated.
Beatrice Belgio, Anna Paola Salvetti, Sara Mantero, Federica Boschetti   +3 more
doaj   +1 more source

Giant Cyst of Dermis-Fat Graft in a Child with MRSA—Case Report

Children
Background/Objectives: This case report presents a unique case of multiple postoperative complications, including sterile silicone implant extrusion, symblepharon formation, and the development of a giant cyst, following extensive multimodal chemotherapy
Biljana Kuzmanović Elabjer, Mirjana Bjeloš, Ana Ćurić, Daliborka Miletić, Mladen Bušić   +4 more
doaj   +1 more source

Inherited retinal diseases in Norway - Studies on phenotype and genotype characteristics

, 2021
Inherited retinal diseases are a leading cause of vision loss in children and young adults. The majority of inherited retinal diseases are untreatable, consequently leading to irreversible retinal damage and blindness.
Holtan, Josephine Prener
core   +1 more source

Diagnostic Role of Chromatic Full-Field Stimulus Test in Rod–Cone Versus Cone Dystrophies

Biomedicines
Background: Inherited retinal dystrophies are a heterogeneous group of progressive disorders impacting photoreceptor function, often limiting the usefulness of standard electroretinography in advanced cases.
Aykut Demirkol, Esra Sahli, Baichun Hou, Promie R. Faruque, Ilay Demirkol, Kuzey Soydas, Stephen H. Tsang   +6 more
doaj   +1 more source

Correction: Combined Genetic and High-Throughput Strategies for Molecular Diagnosis of Inherited Retinal Dystrophies

, 2014
Correction: Combined Genetic and High-Throughput Strategies for Molecular Diagnosis of Inherited Retinal ...
PLOS ONE (2189197)
core   +1 more source

Understanding the expectations of patients with inherited retinal dystrophies

British Journal of Ophthalmology, 2013
UK genetic ophthalmology services for patients with retinal dystrophy (RD) are variable. Little research exists to define service requirements, or expectations, of patients and their families. This study aimed to explore the views and perceived benefits of genetic ophthalmology services among members of families with RD.Twenty participants with known ...
Combs, Ryan, Hall, Georgina, Payne, Katherine; id_orcid 0000-0002-3938-4350, Lowndes, Jo, Devery, Sophie, Downes, Susan M., Moore, Anthony T., Ramsden, Simon, Black, Graeme C M, McAllister, Marion   +9 more
openaire   +2 more sources

Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases

Frontiers in Cell and Developmental Biology, 2018
In recent years, there has been accelerated growth of clustered regularly interspaced short palindromic repeats (CRISPR) genome surgery techniques. Genome surgery holds promise for diseases for which a cure currently does not exist.
Christine L. Xu, Christine L. Xu, Galaxy Y. Cho, Galaxy Y. Cho, Galaxy Y. Cho, Jesse D. Sengillo, Jesse D. Sengillo, Jesse D. Sengillo, Karen S. Park, Karen S. Park, Vinit B. Mahajan, Vinit B. Mahajan, Stephen H. Tsang, Stephen H. Tsang, Stephen H. Tsang, Stephen H. Tsang   +15 more
doaj   +1 more source

Research Models and Gene Augmentation Therapy for CRB1 Retinal Dystrophies

Frontiers in Neuroscience, 2020
Retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA) are inherited degenerative retinal dystrophies with vision loss that ultimately lead to blindness.
Nanda Boon, Jan Wijnholds, Jan Wijnholds, Lucie P. Pellissier   +3 more
doaj   +1 more source

Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence

, 2022
Whether by indirect oxidative stress or direct genetic defect, various genetic retinal dystrophies involve mitochondrial stress. Mitochondrial flavoprotein fluorescence (FPF), reported as either average signal intensity or variability (heterogeneity ...
Elias I. Traboulsi (7928237), Madhukar Kumar (14132848), Justin C. Muste (14132842), Rishi P. Singh (604020), Matthew W. Russell (14132839), Collin A. Rich (14132851), Kanika Seth (14132845)   +6 more
core   +1 more source