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Inhibin and Inhibin-Related Proteins
1993Abstract It has been recognized for many years that the gonads produce a nonsteroidal factor termed inhibin that preferentially suppresses pituitary follicle-stimulating hormone (FSH) secretion. Progress in its isolation, characterization, and clarification of its physiology, however, has only occurred since 1985 after the development
David M Robertson +2 more
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Archives of Andrology, 1980
The bioassays developed so far, although good for detecting inhibin from different sources and for monitoring their purification, are not really practical for physiological studies. Moreover, they are influenced by steroidal hormones. In this regard radioimmunoassays, with their high capacity and greater sensitivity, are of immense value in studies ...
S B, Moodbidri, A Y, Vaze, A R, Sheth
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The bioassays developed so far, although good for detecting inhibin from different sources and for monitoring their purification, are not really practical for physiological studies. Moreover, they are influenced by steroidal hormones. In this regard radioimmunoassays, with their high capacity and greater sensitivity, are of immense value in studies ...
S B, Moodbidri, A Y, Vaze, A R, Sheth
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Reproductive Medicine Review, 1992
Inhibin is a glycoprotein hormone, consisting of two dissimilar, disulphide-linked subunits, termed α (MW 20kD) and β (MW 3-15kD), which inhibits the production and/or secretion of pituitary gonadotrophins, preferentially follicle stimulating hormone (FSH).
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Inhibin is a glycoprotein hormone, consisting of two dissimilar, disulphide-linked subunits, termed α (MW 20kD) and β (MW 3-15kD), which inhibits the production and/or secretion of pituitary gonadotrophins, preferentially follicle stimulating hormone (FSH).
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Journal of Reproductive Immunology, 1998
Previous observations from our laboratory have demonstrated that the levels of immunoreactive inhibin (ir-inh) are elevated in almost all patients with granulosa cell tumors and in the majority of postmenopausal women with mucinous ovarian cancers.
H G, Burger +13 more
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Previous observations from our laboratory have demonstrated that the levels of immunoreactive inhibin (ir-inh) are elevated in almost all patients with granulosa cell tumors and in the majority of postmenopausal women with mucinous ovarian cancers.
H G, Burger +13 more
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1988
Publisher Summary This chapter discusses the isolation, structure, characterization, and biosynthesis of inhibins and activins. The two pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) which regulate the development and maturation of the gonad, are identified.
N, Ling +7 more
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Publisher Summary This chapter discusses the isolation, structure, characterization, and biosynthesis of inhibins and activins. The two pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) which regulate the development and maturation of the gonad, are identified.
N, Ling +7 more
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Pathologie-biologie, 1983
Inhibin is a peptidic gonadal hormone which preferentially suppresses FSH secretion and synthesis. As its purification is not yet achieved, only bioassays are available, performed with testicular extracts or follicular fluid. Its secretion by granulosa cells and Sertoli cells is partly spontaneous, partly stimulated by androgens and FSH.
C, Lefaucheur +3 more
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Inhibin is a peptidic gonadal hormone which preferentially suppresses FSH secretion and synthesis. As its purification is not yet achieved, only bioassays are available, performed with testicular extracts or follicular fluid. Its secretion by granulosa cells and Sertoli cells is partly spontaneous, partly stimulated by androgens and FSH.
C, Lefaucheur +3 more
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1980
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are secreted independently of each other under various physiologic and pathologic conditions (Franchimont and Burger, 1975). Thus, at the onset of the follicular phase of the menstrual cycle, FSH levels are elevated and progressively decrease, while those of LH are very low at the ...
P, Franchimont +4 more
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Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are secreted independently of each other under various physiologic and pathologic conditions (Franchimont and Burger, 1975). Thus, at the onset of the follicular phase of the menstrual cycle, FSH levels are elevated and progressively decrease, while those of LH are very low at the ...
P, Franchimont +4 more
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