Results 321 to 330 of about 4,357,163 (359)
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Oncology Reports, 1996
A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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Seminars in Hematology, 2006
The majority of direct costs associated with caring for patients with hemophilia are attributed to replacement therapy with clotting factor concentrates (CFC). For patients who develop high-titer inhibitors, CFC are ineffective and bypassing therapy is used to achieve hemostasis, thus changing the direct costs associated with treatment.
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The majority of direct costs associated with caring for patients with hemophilia are attributed to replacement therapy with clotting factor concentrates (CFC). For patients who develop high-titer inhibitors, CFC are ineffective and bypassing therapy is used to achieve hemostasis, thus changing the direct costs associated with treatment.
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2016
he use of corrosion inhibitors represents an important option for the control of corrosion processes and for providing corrosion protection to different metals. Inhibitors have been widely used for corrosion control. They can be employed in solution in order to control the aggressiveness of a corrosive media.
ANDREATTA, Francesco, FEDRIZZI, Lorenzo
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he use of corrosion inhibitors represents an important option for the control of corrosion processes and for providing corrosion protection to different metals. Inhibitors have been widely used for corrosion control. They can be employed in solution in order to control the aggressiveness of a corrosive media.
ANDREATTA, Francesco, FEDRIZZI, Lorenzo
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Clinics in Liver Disease, 2009
The percentage of patients chronically infected with hepatitis C virus (HCV) who have reached sustained antiviral response has increased since the introduction of the pegylated interferon-alpha (pIFNa) and ribavirin (RBV) treatment. However, the current standard pIFNa/RBV therapy not only has a low success rate (about 50%) but is often associated with ...
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The percentage of patients chronically infected with hepatitis C virus (HCV) who have reached sustained antiviral response has increased since the introduction of the pegylated interferon-alpha (pIFNa) and ribavirin (RBV) treatment. However, the current standard pIFNa/RBV therapy not only has a low success rate (about 50%) but is often associated with ...
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2012
In May 2003, the US Food and Drug Administration (FDA) granted accelerated approval for the use of the first-in-class proteasome inhibitor bortezomib as a third-line therapy in multiple myeloma, and the European Union followed suit a year later. Bortezomib has subsequently been approved for multiple myeloma as a second-line treatment on its own and as ...
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In May 2003, the US Food and Drug Administration (FDA) granted accelerated approval for the use of the first-in-class proteasome inhibitor bortezomib as a third-line therapy in multiple myeloma, and the European Union followed suit a year later. Bortezomib has subsequently been approved for multiple myeloma as a second-line treatment on its own and as ...
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Trends in kinase drug discovery: targets, indications and inhibitor design
Nature Reviews Drug Discovery, 2021Misty M Attwood, Stefan Knapp
exaly