Results 131 to 140 of about 6,512,999 (388)
Терапевтический архив, 2003 Aim. To study the activity of angiotensin-converting enzyme (ACE) in patients with pneumonia and chronic obstructive lung diseases (COLD). Material and Methods. Sixty nine patients with pneumonia and 77 with COLD were examined. The activity of ACE in the
B Yu Altshuler +8 more
doaj
Advanced Science, 2020 The Rho family GTPases are crucial drivers of tumor growth and metastasis. However, it is difficult to develop GTPases inhibitors due to a lack of well‐characterized binding pockets for compounds.
Zhongya Sun +25 more
doaj +1 more source
A comprehensive review on tyrosinase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning.
S. Zolghadri +6 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Current Pharmaceutical Design, 2013 The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl- channel whose major function is to facilitate epithelial fluid secretion. Loss-of-function mutations in CFTR cause the genetic disease cystic fibrosis. CFTR is required for transepithelial fluid transport in certain secretory diarrheas, such as cholera, and ...
Verkman, Alan S +4 more
openaire +4 more sources
Bacterial Inhibitors for Cutting Oil [PDF]
, 1956 H. O. Wheeler, E. O. Bennett
openalex +2 more sources
Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells [PDF]
, 2015 BRAF inhibitors can extend progression-free and overall survival in melanoma patients whose tumors harbor mutations in BRAF. However, the majority of patients eventually develop resistance to these drugs. Here we show that BRAF mutant melanoma cells that
Baenke, Franziska +12 more
core +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Behaviour of AISI 316L Steel Exposed to Demineralized Water [PDF]
Kemija u Industriji, 2009 The subject of investigation was the passivation of AISI 316L austenitic stainless steel. The effectiveness of various passivation media was tested by means of the potentiodynamic polarization technique.
Kožuh, S., Marijan, D., Gojic, M.
doaj