Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
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Primary Pulmonary NUT Carcinoma: A Case Illustration of Therapeutic Challenges and Review of Emerging Targeted Therapies. [PDF]
Case Rep Oncol MedBae JY, Gao XY, Dermawan JK, Hellyer JA.
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
RET Signaling Pathway in Human Cancer: Oncogenic Mechanisms, Selective Inhibitors, and Emerging Resistance Strategies. [PDF]
Int J Mol SciStreit S +5 more
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Inhibitory influence of three new synthesized cationic gemini surfactants on the corrosion rate of carbon steel in 1 M HCl. [PDF]
Sci RepAbdelhafiz FM +3 more
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Updates in Hospital Medicine: Nephrology. [PDF]
J Brown Hosp MedGarsuta CGL, Mahmoud HM, Gordon LB.
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Treatment of Youth-Onset Type 2 Diabetes: Focus on SGLT-2 Inhibitor Use. [PDF]
Pediatr DiabetesArslanian S, Barrett T, Shehadeh N.
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Metabolic Concepts of Sodium-Glucose Cotransporter 2 Inhibitors-Based Therapies Against Hepatocarcinogenesis and Therapy Resistance in Hepatocellular Carcinoma. [PDF]
Life (Basel)Chung HH.
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