Results 91 to 100 of about 7,577,140 (312)

The Inhibition and Interaction Effect of Whole Grain Highland Barley Extract on α-glucosidase Inhibitory Activity

open access: yesLiang you shipin ke-ji
Highland barley is a unique cereal in the Qinghai-Tibet Plateau of China, and has good effects on improving blood glucose metabolism. However, its specific hypoglycemic ingredients and compatibility are not yet clear. In this manuscript, the polyphenols,
REN Xin   +4 more
doaj   +1 more source

INHIBITORY ACTIVITY OF LACTIC ACID BACTERIA ISOLATED FROM TILAPIA GUT AGAINST STREPTOCOCCUS AGALACTIAE [PDF]

open access: yesAssiut Veterinary Medical Journal
Tilapia culture offers cheap high-quality protein for the human population demand.  However, with intensification, the cultured tilapia become threatened by Streptococcus infection, and antibiotic resistance emergence in aquaculture.
NOURA KELANY   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Synthesis, Anticancer Evaluation and Molecular Docking studies of Novel Benzophenone based 1,2,3-Triazole Hybrids [PDF]

open access: yesJournal of Chemistry Letters
A series of novel benzophenone based1,2,3-triazole hybrids (8a-l) were synthesized. The biological screening of these compounds was performed on antibacterial, antioxidant, and cytotoxic activity (HT-1080, A-549 cell lines).Compounds 8d, 8h, and 8l are ...
Venkateswara Rao Battula   +6 more
doaj   +1 more source

α-Glucosidase inhibitory activity of catechin and PCG.

open access: yes, 2016
α-Glucosidase inhibitory activity of catechin and PCG.
Benguo Liu (2557657)   +3 more
core   +1 more source

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria [PDF]

open access: yes, 2010
Background: Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated as potential alternative ...
Han Haley   +47 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Different Combinations of Nitrogen and Carbon Sources Influence the Growth and Postbiotic Metabolite Characteristics of Lactiplantibacillus plantarum Strains Isolated from Malaysian Foods

open access: yesFoods
Postbiotic metabolites produced by Lactiplantibacillus plantarum strains isolated from Malaysian food have been extensively reported for their positive effects on health.
Qinri Zheng   +5 more
doaj   +1 more source

α-Glucosidase inhibitory activity of triazoloquinazolines 1–14.

open access: yes, 2019
α-Glucosidase inhibitory activity of triazoloquinazolines 1–14.
Hatem A. Abuelizz (6160082)   +5 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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