Results 71 to 80 of about 1,093,974 (259)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Dissociable yet tied inhibitory processes: The structure of inhibitory control

Cognitive, Affective, & Behavioral Neuroscience, 2014
Cognitive and neural models have proposed the existence of a single inhibitory process that regulates behavior and depends on the right frontal operculum (rFO). The aim of this study was to make a contribution to the ongoing debate as to whether inhibition is a single process or is composed of multiple, independent processes.
Michael, George A., Mizzi, Raphaël, Couffe, Cyril, Gálvez García, Germán   +3 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A meta-analysis of the dose–response relationship between aerobic exercise and executive function in children

Frontiers in Public Health
ObjectiveWhile existing meta-analyses of executive function focus on older adults and clinical pediatric populations, a substantial gap remains regarding typically developing children during this critical period.
Yanhua Wang, Qi Wang, Min Yang, Wenwen Li, Lu Wang, Jiaqi Fan   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Nutritional habits, inhibitory control, and emotional reactivity to healthy and unhealthy food cues in non-obese female students: insights from heart rate variability

Frontiers in Nutrition
BackgroundResearch shows that the nutritional habits of university students do not follow the national recommendations. While most studies have focused on the increased risk of overweight/obesity, avoiding unhealthy food or maintaining a normal weight ...
Michela Sarlo, Fiorella Del Popolo Cristaldi, Giulia Buodo, Carmen Belacchi   +3 more
doaj   +1 more source

The Effect of an Acute Aerobic Exercise with Different Intensities on the Executive Functions of 9-10-year-old Children [PDF]

International Journal of School Health
Background: It is well-established that executive function can be affected by a session of aerobic training. Our study aimed to determine how acute aerobic exercise affect executive function at different intensities in 9-10-year-old children.Methods: The
Bayan Amani, Arezo Ahmadpour, Mohammad Rahman Rahimi   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The interference effect of concurrent working memory task on visual inhibitory control

Journal of Eye Movement Research, 2016
We examined the interference between inhibitory control of a saccadic eye movement and a working memory task. This study was motivated by the observation that people are suscep-tible to cognitive errors when they are preoccupied. Subjects were instructed
Brad M. Hong, Susan Weiner, Michael Clancy, Minjoon Kouh   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source