Results 71 to 80 of about 1,142,444 (260)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The role of 24-h movement Behaviors in preschool children’s learning ability: the mediating effect of inhibitory control

Frontiers in Psychology
PurposeTo investigate the impact of 24-h movement behaviors—sleep (SP), sedentary behavior (SB), light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)—on preschool children’s learning ability, with emphasis on inhibitory ...
Chang Zhenya, Huang Jia
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effect of Computer-assisted Neurocognitive Rehabilitation on Inhibitory Control of the Students With Dyscalculia

Iranian Rehabilitation Journal, 2017
Objectives: Cognitive functions are the most important factors that influence the performances of students with dyscalculia. This study investigates the effect of computer-assisted neurocognitive rehabilitation on the inhibitory control of students with ...
Fatemeh Bazzaz Monsef, Mehran Soleymani, Behzad Shalchi   +2 more
doaj  

A meta-analysis of the dose–response relationship between aerobic exercise and executive function in children

Frontiers in Public Health
ObjectiveWhile existing meta-analyses of executive function focus on older adults and clinical pediatric populations, a substantial gap remains regarding typically developing children during this critical period.
Yanhua Wang, Qi Wang, Min Yang, Wenwen Li, Lu Wang, Jiaqi Fan   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Nutritional habits, inhibitory control, and emotional reactivity to healthy and unhealthy food cues in non-obese female students: insights from heart rate variability

Frontiers in Nutrition
BackgroundResearch shows that the nutritional habits of university students do not follow the national recommendations. While most studies have focused on the increased risk of overweight/obesity, avoiding unhealthy food or maintaining a normal weight ...
Michela Sarlo, Fiorella Del Popolo Cristaldi, Giulia Buodo, Carmen Belacchi   +3 more
doaj   +1 more source

The Effect of an Acute Aerobic Exercise with Different Intensities on the Executive Functions of 9-10-year-old Children [PDF]

International Journal of School Health
Background: It is well-established that executive function can be affected by a session of aerobic training. Our study aimed to determine how acute aerobic exercise affect executive function at different intensities in 9-10-year-old children.Methods: The
Bayan Amani, Arezo Ahmadpour, Mohammad Rahman Rahimi   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Adolescent predisposition to binge drinking is associated with differences in inhibitory control MEG event-related fields

Frontiers in Psychiatry
IntroductionAdolescent binge drinking (BD) is a major public health concern, yet little is known about the neural markers that precede alcohol initiation.
Luis Fernando Antón-Toro, Luis Fernando Antón-Toro, Danylyna Shpakivska-Bilan, Danylyna Shpakivska-Bilan, Lucía López-Abad, Lucía López-Abad, Alberto Del Cerro-León, Alberto Del Cerro-León, Marcos Uceta, Marcos Uceta, Ricardo Bruña, Ricardo Bruña, Luis M. García-Moreno, Fernando Maestú, Fernando Maestú   +14 more
doaj   +1 more source