Results 101 to 110 of about 3,130,649 (266)
Initial-Condition Dependence and Initial-Condition Uncertainty in Climate Science
The British Journal for the Philosophy of Science, 2019 This article examines initial-condition dependence and initial-condition uncertainty for climate projections and predictions. The first contribution is to provide a clear conceptual characterization of predictions and projections. Concerning initial-condition dependence, projections are often described as experiments that do not depend on initial ...
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Developing initial conditions for simulations of asymmetric membranes: a practical recommendation. [PDF]
Biophys J, 2021 Park S, Im W, Pastor RW.
europepmc +1 more source
Dependence upon initial conditions
Communications in Nonlinear Science and Numerical Simulation, 2019 This article discusses dependence on initial conditions in natural and social sciences with focus on physical science. The main focus is on the newly discovered rough dependence on initial data.
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Examination of sub-harmonic responses along with various initial conditions induced by multi-staged clutch damper system. [PDF]
Sci Rep, 2022 Yoon JY, Kim B.
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Baltic sea deep salinity: an initial and boundary value problem
Frontiers in Earth ScienceThe Baltic Sea salinity is modelled using a two-box model. The simplistic approach allows for very long integrations where a large part of the phase space of the model can be probed. Particular emphasis is put on the salinity dynamics in the deeper parts
Magnus Hieronymus
doaj +1 more source
Assessing the role of initial conditions in the local structural identifiability of large dynamic models. [PDF]
Sci Rep, 2021 Joubert D, Stigter JD, Molenaar J.
europepmc +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source