Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Initial development and sample dimensioning of rubber tree clones
Bioscience Journal, 2018 The current success of rubber cultivation is related to the use of clones adapted to different edaphoclimatic regions. Hence, it is important to evaluate variables that are correlated with yield. However, a common problem is choosing the plot dimensions
Victor Hugo Santi de Oliveira +6 more
doaj
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Allocation of Land at the Rural-Urban Fringe Using a Spatially-Realistic Ecosystem Constraint [PDF]
Development in rural-urban fringe communities is increasing with the potential to damage healthy ecosystems and endanger the long-term persistence of resident flora and fauna.
Bauer, Dana Marie, Swallow, Stephen K.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
NEW ABOUT THE INITIAL STAGES OF EMBRYONIC HUMAN DEVELOPMENT
Мать и дитя в Кузбассе, 2018 The objective of the study was to up-date the information on the initial stages of human embryonic development to the stage of blastocyst. Methodology of the study. We used databases: Cochrane, Medline, PubMed, HINARY.
Максим Владимирович Додонов +1 more
doaj
Initial Development of an Immediate Implantation Model in Rats and Assessing the Prognostic Impact of Periodontitis on Immediate Implantation. [PDF]
Bioengineering (Basel), 2023 Wang Y +8 more
europepmc +1 more source
Reusable Centaur study. Volume 1: Executive summary [PDF]
A study of the Reusable Centaur for use as an initial upper stage with the space shuttle was conducted. The currently operative Centaur stage, with modifications for space shuttle orbiter compatibility and for improved performance, represents a cost ...
Heald, D. A.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Original research: initial development of a pragmatic tool to estimate cognitive decline risk focusing on potentially modifiable factors in Parkinson's disease. [PDF]
Front Neurosci, 2023 Carlisle TC, Medina LD, Holden SK.
europepmc +1 more source