Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Initial development and validation of a disease-specific resilience measure for inflammatory bowel disease: the RISE-IBD instrument. [PDF]
Mendiolaza M +6 more
europepmc +1 more source
Initial Development of a Patient Reported Experience Measure for Older Adults Attending the Emergency Department: Part I-Interviews with Service Users. [PDF]
Graham B +4 more
europepmc +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Initial Development of the Nurse Perception of Infant Condition (NPIC) Scale. [PDF]
Fortney CA +5 more
europepmc +1 more source
Corrigendum: Initial development of perpetrator confrontation using deepfake technology in victims with sexual violence-related PTSD and moral injury. [PDF]
van Minnen A +5 more
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Initial Development of a Patient-Reported Experience Measure for Older Adults Attending the Emergency Department: Part II-Focus Groups with Professional Caregivers. [PDF]
Graham B +4 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Relative victimization scale: initial development and retrospective reports of the impact on mental health. [PDF]
Belen H.
europepmc +1 more source

