Results 41 to 50 of about 1,168,780 (297)

Faint Stars in a Faint Galaxy. II. The Low-mass Stellar Initial Mass Function of the Boötes I Ultrafaint Dwarf Spheroidal Galaxy

The Astrophysical Journal, 2022
This paper presents improved constraints on the low-mass stellar initial mass function (IMF) of the Boötes I (Boo I) ultrafaint dwarf galaxy, based on our analysis of recent deep imaging from the Hubble Space Telescope.
Carrie Filion, Imants Platais, Rosemary F. G. Wyse, Vera Kozhurina-Platais   +3 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

THE HIGH-MASS STELLAR INITIAL MASS FUNCTION IN M31 CLUSTERS [PDF]

The Astrophysical Journal, 2015
We have undertaken the largest systematic study of the high-mass stellar initial mass function (IMF) to date using the optical color-magnitude diagrams (CMDs) of 85 resolved, young (4 Myr < t < 25 Myr), intermediate mass star clusters (10^3-10^4 Msun), observed as part of the Panchromatic Hubble Andromeda Treasury (PHAT) program.
Daniel R. Weisz, L. Clifton Johnson, Daniel Foreman-Mackey, Andrew E. Dolphin, Lori C. Beerman, Benjamin F. Williams, Julianne J. Dalcanton, Hans-Walter Rix, David W. Hogg, Morgan Fouesneau, Benjamin D. Johnson, Eric F. Bell, Martha L. Boyer, Dimitrios Gouliermis, Puragra Guhathakurta, Jason S. Kalirai, Alexia R. Lewis, Anil C. Seth, Evan D. Skillman   +18 more
openaire   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

A Comparison of Full Spectral Fitting Codes for Measuring the Stellar Initial Mass Function and Other Stellar Population Properties in Elliptical Galaxies

The Astrophysical Journal
We present a comparative test of four widely used full spectral fitting codes, with the aim of answering the question: How robust is the retrieval of the stellar initial mass function (IMF) and other stellar properties of galaxies?
Ilaria Lonoce, Anja Feldmeier-Krause, Alexandra Masegian, Wendy L. Freedman   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Dusty Disks at the Bottom of the Initial Mass Function [PDF]

The Astrophysical Journal, 2007
Isolated planetary-mass objects (IPMOs) have masses close to or below the deuterium-burning mass limit (∼ )—at the bottom of the stellar initial mass function . We present an exploratory survey for disks in this 15 MJup mass regime, based on a dedicated observing campaign with the Spitzer Space Telescope.
Scholz, Alexander, Jayawardhana, Ray
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Low-mass Stellar Initial Mass Function in Nearby Ultrafaint Dwarf Galaxies

The Astrophysical Journal
The stellar initial mass function (IMF) describes the distribution of stellar masses that form in a given star formation event. The long main-sequence lifetimes of low-mass stars mean that the IMF in this regime (below ∼ 1 M _⊙ ) can be investigated ...
Carrie Filion, Rosemary F. G. Wyse, Hannah Richstein, Nitya Kallivayalil, Roeland P. van der Marel, Elena Sacchi   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source