Results 71 to 80 of about 143,267 (285)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Impact of the Initial State on BDS Real-Time Orbit Determination Filter Convergence

Remote Sensing, 2018
High precision real-time orbit of navigation satellites are usually predicted based on batch estimation solutions, which is highly dependent on the accuracy of the dynamic model.
Yun Qing, Yidong Lou, Yang Liu, Xiaolei Dai, Yi Cai   +4 more
doaj   +1 more source

Toward Accurate Physics‐Based Specifications of Neutral Density Using GNSS‐Enabled Small Satellites

Space Weather, 2021
Satellite‐atmosphere interactions cause large uncertainties in low‐Earth orbit determination and prediction. Thus, knowledge of and the ability to predict the space environment, most notably thermospheric mass density, are essential for operating ...
Eric K. Sutton, Jeffrey P. Thayer, Marcin D. Pilinski, Shaylah M. Mutschler, Thomas E. Berger, Vu Nguyen, Dallas Masters   +6 more
doaj   +1 more source

Orbit determination of Transneptunian objects and Centaurs for the prediction of stellar occultations

, 2015
The prediction of stellar occultations by Transneptunian objects and Centaurs is a difficult challenge that requires accuracy both in the occulted star position as for the object ephemeris.
Assafin, M., Benedetti-Rossi, G., Braga-Ribas, F., Camargo, J. I. B., Colas, F., Desmars, J., Duffard, R., Gomes-Júnior, A. R., Morales, N., Ortiz, J. L., Sicardy, B., Vachier, F., Vieira-Martins, R.   +12 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Revising the age for the Baptistina asteroid family using WISE/NEOWISE data [PDF]

, 2012
We have used numerical routines to model the evolution of a simulated Baptistina family to constrain its age in light of new measurements of the diameters and albedos of family members from the Wide-field Infrared Survey Explorer. We also investigate the
A. K. Mainzer, Broz˘, Carry, J. M. Bauer, Joseph R. Masiero, Mainzer, Mainzer, Mainzer, Masiero, Morbidelli, Morbidelli, Nesvorný, Nesvorný, R. Jedicke, T. Grav, Tedesco, Vokrouhlický, Vokrouhlický, Vokrouhlický, Wright   +19 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Effects of the Planar Galactic Tides and Stellar Mass on Comet Cloud Dynamics

, 2009
We report the first results of a research program to explore the sensitivity of the orbits of Oort cloud comets to changes in the strength of the Galactic tides in the plane of the disk and also to changes in the mass of the host star.
Gonzalez, Guillermo, Masi, Marco, Secco, Luigi   +2 more
core   +1 more source