Results 91 to 100 of about 4,499,219 (309)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Orbit Determination Error Analysis for a future Space Debris Tracking Radar [PDF]
, 2011 Independent of light and weather conditions radar systems provide observations of space debris in low and medium earth orbits. In general two operational principles can be distinguished - in survey mode all objects passing through the radar instrument ...
Patyuchenko, Anton, Weigel, Martin
core
, 2023 openPrecise Orbit Determination (POD) has become more and more relevant over the past decades due to the ever increasing requirements artificial satellites must satisfy. This is true for both commercial and scientific missions that find applications in a
FIORESE, LORENZO
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Orbit Precision Analysis of Small Man-Made Space Objects in LEO Based on Radar Tracking Measurements [PDF]
, 2012 The German Space Operations Center (GSOC) performs collision avoidance for 11 LEO and 2 GEO satellites. Risk detection and maneuver decisions strongly depend on the computed probability of collision that is driven by the anticipated orbit precision of ...
Letsch, Klemens +6 more
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Geo-spatial Information SciencePrecise orbit determination of near-Earth asteroids (NEAs) provides a critical foundation for exploration missions. Considering that cislunar space is a critical domain for future human space activities and the unique positional advantage of the Earth ...
Zhenqi Wang +7 more
doaj +1 more source
Coplanar Maneuvers Transfer for Mission Design with Lowest ∆ʋ using Series Solution [PDF]
Kirkuk Journal of Science, 2015 Orbital maneuver transfer time is traditionally accomplished using direct numerical sampling to find the mission design with the lowest delta-ʋ requirements.
Mayada J. Hamwdi +2 more
doaj +1 more source
Initial Relative Orbit Determination Using Heterogeneous TDOA
, 2017 This paper presents a solution for the initial orbit determination of a space-based RF transmitter using time-difference-of-arrival (TDOA) measurements obtained from space-based receivers in known orbits. Orbit determination requires six independent TDOA
Sinclair, Andrew J. +5 more
core +1 more source