Results 111 to 120 of about 4,499,219 (309)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Initial orbit determination and satellite tracking using optical observations

, 2021
The objective of this project is to propose a passive method for orbit determination (OD) of GEO objects using observational data as position measurements. The proposed method use position measurements expressed as right ascension and declination angles,
Aizcorbe Rodriguez, Carlos
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Initial Values Determination of Thrust Parameters for Continuously Low-Thrust Maneuvering Spacecraft

Applied Sciences
Continuous low thrust is widely used in orbit transfer maneuvers. If the unknown maneuvers are not correctly compensated, the orbiting accuracy will be seriously affected.
Wen Guo, Xuefeng Tao, Min Hu, Wen Xue
doaj   +1 more source

Precise Orbit Determination

, 2017
Precise Orbit Determination (POD) is an integral part for analyzing measurements from space geodetic techniques such as Satellite Laser Ranging (SLR) and Global Navigation Satellite Systems (GNSS) such as the Global Positioning System (GPS).
Arnold, Daniel, Daniel Arnold, Adrian Jäggi, Jäggi, Adrian   +3 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Initial Orbit Determination of a Space Object from Limited Angular Optical Measurements

Приборы и методы измерений
Currently, the problem of initial orbit determination for space objects based on angular coordinate measurements (right ascension and declination) under limited data conditions is of significant practical value.
V. S. Baranova, A. A. Spiridonov, D. V. Ushakov, V. A. Saetchnikov   +3 more
doaj   +1 more source

A Method to Determine BeiDou GEO/IGSO Orbital Maneuver Time Periods

Sensors, 2019
Because there are different types of BeiDou constellations with participating geostationary orbit (GEO) and inclined geosynchronous orbit (IGSO) satellites, the maneuvering frequency of BeiDou satellites is higher than that of other navigation systems ...
Zhiwei Qin, Guanwen Huang, Qin Zhang, Le Wang, Xingyuan Yan, Yanchao Kang, Xiaolei Wang, Shichao Xie   +7 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source