Results 101 to 110 of about 4,499,219 (309)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

DETERMINATION OF INITIAL CONDITIONS FOR SATELLITE FORMATION ELYING IN ELLIPTICAL ORBITS

open access: yesJournal of Astronomy and Space Sciences, 2005
The initial conditions that generate bounded motion in eccentric reference orbit are determined for satellite formation flying. Because Hill's equations cannot describe the relative motion between two satellites in eccentric orbit, a new relative dynamics utilizing the nonlinearity and eccentricity correction for Hill's initial conditions is ...
Woo-Kyoung Lee   +4 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

COSMIC-2 Precise Orbit Determination [PDF]

open access: yes, 2019
We present initial results for post-processed GNSS orbit and clock estimation for the FORMOSAT-7/COSMIC-2 (Constellation Observing System for Meteorology, Ionosphere, and Climate) constellation.
Arnold, Daniel   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Space-Based Orbit Determination Using Passive Optical Measurements in LEO [PDF]

open access: yes
openThe increasing number of artificial objects placed in Low Earth Orbit (LEO) has created the need for improvement in the present Space Surveillance and Tracking (STT) systems, which perform Orbit Determination (OD) to estimate their trajectories ...
CABRERA GARCIA, JUAN FELIPE
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Autonomous Orbit Determination of LLO Satellite Using DRO–LLO Links and Lunar Laser Ranging

open access: yesAerospace
A stable and high-precision autonomous orbit determination scheme for a Low Lunar Orbit (LLO) spacecraft is proposed, leveraging satellite-to-satellite tracking (SST) measurement data and lunar laser ranging data.
Shixu Chen   +4 more
doaj   +1 more source

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