Results 91 to 100 of about 4,858,701 (299)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The dynamics of New Zealand commercial property portfolios

open access: yes, 2005
The dynamics of commercial property portfolio peljormance in New Zealand have changed considerably in recent years, with most of these dynamics working in favour of commercial property in an investment portfolio.
Newell, Graeme
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Penerapan Fungsi Sosial Terhadap Hak Kekayaan Intelektual Di Dalam Masyarakat

open access: yesNagari Law Review, 2019
This article analyzes the position of ideal social functions in IPR which should be regulated by the government. The purpose of writing this article is to examine the social functions of the government to overcome the conflicting intellectual property ...
Chandra Yusuf, Nelly Ulfah Anisariza
doaj   +1 more source

Property Council of Australia federal pre-budget submission 2016-17

open access: yes, 2016
Property touches the lives of all Australians. It creates prosperity, jobs and strong communities. Property is both a major part of the household balance sheet and the Australian economy.
Property Council of Australia
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Initial Psychometric Properties of the Adaptive Suicide Cognitions Scale

open access: yesArchives of Suicide Research
Individuals who have experienced suicidal thoughts or behaviors report experiencing stigma from social contacts as well as treatment providers. Stigma is, in turn, associated with worse outcomes, including increases in suicidal ideation. Although some research has measured experiences of stigma related to suicide, tools measuring destigmatizing or ...
Erik J. Reinbergs   +3 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

‘ReLIC: Reduced Logic Inference for Composition’ for Quantifier Elimination‐Based Compositional Reasoning and Verification

open access: yesIET Cyber-Physical Systems
Formally verifying complex model‐based designs has posed a significant challenge for complex systems, primarily due to their sheer scale and the critical nature of safety involved.
Hao Ren, Ratnesh Kumar
doaj   +1 more source

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