Results 71 to 80 of about 1,236,639 (263)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

An s-version finite element method without generation of coupling stiffness matrix by using iterative technique

Mechanical Engineering Journal, 2016
In s-version finite element method (s-FEM) proposed by Fish (1992), a local mesh that represents the local feature such as a hole or a crack is superposed on a global mesh that represents the shape of the whole analysis model.
Yosuke YUMOTO, Yasunori YUSA, Hiroshi OKADA   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Thermomagnetic effect on the propagation of Rayleigh waves in an isotropic homogeneous elastic half-space under initial stress

Cogent Engineering, 2015
Rayleigh wave propagation in an isotropic homogeneous initially stressed thermoelastic half-space under the effect of magnetic field has been studied using Green–Lindsay (GL) theory of generalized thermoelasticity.
Rajeev Ghatuary, Nilratan Chakraborty
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dispersion of Love wave in an isotropic layer sandwiched between orthotropic and prestressed inhomogeneous half-spaces

Latin American Journal of Solids and Structures
An in-depth study has been carried out for the dispersion of Love waves in an isotropic elastic layer sandwiched between orthotropic and prestressed inhomogeneous elastic half-spaces.
Rajneesh Kakar
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

On Two Dimensional Dynamical Analysis Of A Pre-stressed Anisotropict Plate-strip With Finite Length

MANAS: Journal of Engineering, 2016
In this study, the influence of initial stress on a pre-stressed orthotropic plate-strip with finite length resting on a rigid half plane is investigated by utilizing Three-Dimensional Linearized Theory of Elastic Waves in Initially Stressed Bodies.
M. Eröz, D. Şimşek
doaj