Results 41 to 50 of about 1,052,374 (268)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Characterizing the respiratory muscle strength of male British Army infantry recruits

open access: yesPhysiological Reports
This study aimed to quantify respiratory muscle strength in infantry recruits during the Phase 1 Combat Infantry Course (CIC) to identify if respiratory muscle weakness was present. Seventy‐six British Army infantry recruits volunteered to participate in
N. C. Armstrong   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

PIBID EM “HORA DO JOGO”: REFLEXÕES SOBRE AS MEDIAÇÕES COM JOGOS DE ALFABETIZAÇÃO EM TURMAS DO PRIMEIRO ANO DO ENSINO FUNDAMENTAL

open access: yesTerra de Pretos, 2020
This article is an experience report on the use of literacy games as a didactic strategy for initial learning of reading and writing, carried out by a group of scholarship students from the Institutional Scholarship Program for Teaching Initiation (Pibid/
Daniela Montuani   +2 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Dimensiones de la tecnología en la formación inicial de profesores de matemáticas: un estudio desde el currículum oficial

open access: yesEcomatemático, 2016
Implementation of technology in teaching-learning mathematics requires a change in teaching practice. This change can be promoted from the initial training of mathematics teachers.
Judith Hernández-Sánchez   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

L’adoption de l’approche par compétence par les enseignants

open access: yesThe Journal of Quality in Education, 2019
L’approche par compétence « APC » est considérée comme l’une des approches pédagogiques les plus appropriées pour un apprentissage efficace. Cependant, bien qu’elle soit de plus en plus recommandée par le système éducatif marocain, on constate une ...
ABDELALI ARBIA   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Concevoir une séquence d’enseignement-apprentissage de l’adjectif : pièges et difficultés en formation initiale

open access: yesLidil
Our contribution analyses the traces of students undergoing initial teacher training for primary teaching. In writings on the preparation of sequences on the adjective and extracts from their research dissertations, we observe how novice teachers deal ...
Annette Schmehl-Postaï
doaj   +1 more source

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