Results 101 to 110 of about 6,303,126 (332)

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague   +8 more
wiley   +1 more source

A hyperbolic problem with nonlinear second-order boundary damping

open access: yesElectronic Journal of Differential Equations, 1998
The initial boundary value problem for the wave equation with nonlinear second-order dissipative boundary conditions is considered. Existence and uniqueness of global generalized solutions are proved.
G. G. Doronin, N. A. Larkin, A. J. Souza
doaj  

A Two-Dimensional Nonlocal Fractional Parabolic Initial Boundary Value Problem

open access: yesAxioms
In this paper, we investigate a two-dimensional singular fractional-order parabolic partial differential equation in the Caputo sense. The partial differential equation is supplemented with Dirichlet and weighted integral boundary conditions.
Said Mesloub   +2 more
doaj   +1 more source

INITIAL VALUE PROBLEM FOR FRACTIONAL ORDER EQUATION WITH CONSTANT COEFFICIENTS

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2016
In this paper we construct an explicit representation of the solution of the Cauchy problem for ordinary differential equation of fractional order with Dzhrbashyan-Nersesyan operators.
Bogatyreva F. T.
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

Extremal Solutions for a Caputo-Type Fractional-Order Initial Value Problem

open access: yesFractal and Fractional
In this paper, we study the existence of extremal solutions for a Caputo-type fractional-order initial value problem. By using the monotone iteration technique and the upper–lower solution method, we obtain our existence theorem when the nonlinearity ...
Keyu Zhang   +3 more
doaj   +1 more source

The Initial Value Problem in Light of Ashtekar's Variables [PDF]

open access: green, 1956
Riccardo Capovilla   +2 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

Hille–Yosida-Type Theorem for Fractional Differential Equations with Dzhrbashyan–Nersesyan Derivative

open access: yesFractal and Fractional
It is a well-known fact that the Dzhrbashyan–Nersesyan fractional derivative includes as particular cases the fractional derivatives of Riemann–Liouville, Gerasimov–Caputo, and Hilfer.
Vladimir E. Fedorov   +4 more
doaj   +1 more source

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