Results 31 to 40 of about 4,524,493 (325)

A parabolic differential equation with unbounded piecewise constant delay

International Journal of Mathematics and Mathematical Sciences, 1992
A partial differential equation with the argument [λt] is studied, where [•] denotes the greatest integer function. The infinite delay t−[λt] leads to difference equations of unbounded order.
Joseph Wiener, Lokenath Debnath
doaj   +1 more source

Solution of Fuzzy Initial Value Problem Using Variational Iteration Method [PDF]

Engineering and Technology Journal, 2014
Variation iteration method is powerful analytical method for solving linear and nonlinear equations. In this paper, the variational iteration method has been applied to solve fuzzy linear and nonlinear differential equations with fuzzy initial conditions,
Marwa Mohamed Esmaeil
doaj   +1 more source

A moving boundary model motivated by electric breakdown: II. Initial value problem [PDF]

, 2009
An interfacial approximation of the streamer stage in the evolution of sparks and lightning can be formulated as a Laplacian growth model regularized by a 'kinetic undercooling' boundary condition.
Arrayás, Arrayás, Ben-Amar, Ben-Amar, Bensimon, Bensimon, Brau, C.-Y. Kao, Cummings, DeGregoria, Derks, Ebert, Ebert, Ebert, F. Brau, Fokas, Homsy, Howison, Howison, Iserles, Kessler, L. Schäfer, Lozansky, Luque, Luque, Mahadevan, Meulenbroek, Meulenbroek, Nie, Pelcé, Reissig, S. Tanveer, Saffman, Sämmer, Tanveer, Tanveer, Tanveer, U. Ebert   +37 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The characteristic initial value problem for colliding plane waves: The linear case [PDF]

, 2002
The physical situation of the collision and subsequent interaction of plane gravitational waves in a Minkowski background gives rise to a well-posed characteristic initial value problem in which initial data are specified on the two null characteristics ...
Griffiths, J. B., Santano-Roco, M.
core   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Light-Front Quantisation as an Initial-Boundary Value Problem

, 1993
In the light front quantisation scheme initial conditions are usually provided on a single lightlike hyperplane. This, however, is insufficient to yield a unique solution of the field equations.
C. Dietmaier, E. Werner, F.G. Friedlander, G. Domokos, G. McCartor, G.'t Hooft, H. Leutwyler, H.C. Pauli, I.M. Gelfand, I.S. Gradshteyn, J. Schwinger, J.D. Bjorken, J.M. Namys?owski, K. Sundermeyer, L. Banyai, L. Faddeev, N.N. Bogolubov, P. Jordan, P.A.M. Dirac, P.A.M. Dirac, P.M. Morse, R. Courant, R. Jackiw, R.A. Neville, R.J. Perry, S. Fubini, S. Schlieder, S. Schweber, S.J. Chang, S.J. Chang, T. Heinzl, T. Heinzl, T. Heinzl, T. Heinzl, T. Myint-U, T. Suzuki   +35 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Smoothness of solutions of conjugate boundary-value problems on a measure chain

Electronic Journal of Differential Equations, 2000
In this paper we consider the n-th order $Delta$-differential equation (often refered to as a differential equation on a measure chain) $$u^{Delta_n}(t) = f(t, u(sigma(t)),dots, u^{Delta_{n-1}}(sigma(t)))$$ satisfying n-point conjugate boundary ...
Eric R. Kaufmann
doaj  

The Initial Value Problem Using Metric and Extrinsic Curvature

, 2004
The initial value problem is introduced after a thorough review of the essential geometry. The initial value equations are put into elliptic form using both conformal transformations and a treatment of the extrinsic curvature introduced recently.
York, James W.
core   +1 more source