Results 91 to 100 of about 29,516 (268)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fast initialization of level set method and an improvement to chan-vese model

open access: yes, 2004
The initialization is an important step in the level set method. However it is a computational time-consuming step. In order to speed up the level set evolution procedures, we first introduce a new initialization algorithm based on the vector distance ...
Wu XJ(吴晓军)   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Experiment design for initialization.

open access: yes, 2016
Experiment design for initialization.
Manzhu Yu (623546)   +1 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Unveiling the Fundamental Principles of Reconfigurable Resistance States in Silver/Poly(Ethylene Glycol) Nanofluids

open access: yesAdvanced Science
Developing novel memristive systems aims to implement key principles of biological neuron assemblies – plasticity, adaptivity, and self‐organization – into artificial devices for parallel, energy‐efficient computing.
Daniil Nikitin   +19 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Similarity between k and l in the original initialization and advanced initialization.

open access: yes, 2018
Similarity between k and l in the original initialization and advanced initialization.
Xiaoping Zhou (453164)   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

WorkflowSim messages—Initialization stage.

open access: yes, 2017
WorkflowSim messages—Initialization stage.
Rocío P. Prado (3639352)   +4 more
core   +1 more source

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