Results 91 to 100 of about 29,516 (268)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fast initialization of level set method and an improvement to chan-vese model
The initialization is an important step in the level set method. However it is a computational time-consuming step. In order to speed up the level set evolution procedures, we first introduce a new initialization algorithm based on the vector distance ...
Wu XJ(吴晓军) +3 more
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Experiment design for initialization.
Experiment design for initialization.
Manzhu Yu (623546) +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Developing novel memristive systems aims to implement key principles of biological neuron assemblies – plasticity, adaptivity, and self‐organization – into artificial devices for parallel, energy‐efficient computing.
Daniil Nikitin +19 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Similarity between k and l in the original initialization and advanced initialization.
Similarity between k and l in the original initialization and advanced initialization.
Xiaoping Zhou (453164) +5 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
WorkflowSim messages—Initialization stage.
WorkflowSim messages—Initialization stage.
Rocío P. Prado (3639352) +4 more
core +1 more source

