Aldehyde Dehydrogenase, a Therapeutic Target in Chordoma: Analysis in 3D Cellular Models
Cells, 2021 Chordomas are rare, slow-growing tumors of the axial skeleton. These tumors are locally aggressive and refractory to conventional therapies. Radical surgery and radiation remain the first-line treatments.
Marie-Anaïs Locquet +13 more
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Nutritional indicators' performance in malnutrition diagnosis of hospitalized elderly patients
Experimental Gerontology, 2023 Background: Several nutritional diagnosis methods and their relationship with clinical outcomes have been described. This study investigated malnutrition in hospitalized elderly patients (HEP) using different nutritional indicators and determined ...
Vânia Aparecida Leandro-Merhi +3 more
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Influence of electronic media on food choices of schoolchildren and adolescents in Luanda, Angola
NAJFNR, 2023 Background: Malnutrition in Angola has reached a prevalence of 17.3 %. On the other hand, the prevalence of childhood obesity is 2.4 %. There has been a food transition in Sub-Saharan Africa, and 28% of consumers obtain their products under the ...
Olineid de Oliveira, Marli Stela Santana
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A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis
Cell Reports, 2016 Melanoma is one of the most lethal cutaneous malignancies, characterized by chemoresistance and a striking propensity to metastasize. The transcription factor ATF2 elicits oncogenic activities in melanoma, and its inhibition attenuates melanoma ...
Giuseppina Claps +15 more
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Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer
Frontiers in Endocrinology, 2017 Oncogenic mutations, such as Ras mutations, drive not only enhanced proliferation but also the metabolic adaptations that confer to cancer cells the ability to sustain cell growth in a harsh tumor microenvironment.
Maria Victoria Recouvreux +1 more
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A Brief Executive Language Screen for Frontal Aphasia
Brain Sciences, 2021 Aphasia assessment tools have primarily focused on classical aphasia type and severity, with minimal incorporation of recent findings that suggest a significant role of executive control operations in language generation.
Gail A. Robinson +3 more
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Schizophrenia long-acting antipsychotics initiation index (SLAAII)
European Psychiatry, 2021 Introduction Background In individuals with schizophrenia, long-acting injectable antipsychotics (LAIs) have been shown to be beneficial in preventing relapse.
P. Ifteni, A. Teodorescu
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The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations
Nature Communications, 2021 Chromosomal translocations involving the AF10 gene, especially with CALM, are associated with aggressive leukemias. Here the authors show that the PZP domain of AF10, a histone reader, is always excluded/impaired in AF10 fusions, whereas incorporation of
Brianna J. Klein +16 more
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Mismatch negativity in patients with (central) auditory processing disorders
Brazilian Journal of Otorhinolaryngology, 2008 Summary: Mismatch Negativity (MMN) is a long-latency auditory evoked potential that provides an objective index of discrimination skills and auditory sensorial memory.
Simone Mariotto Roggia +1 more
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Ribosome Biogenesis Alterations in Colorectal Cancer
Cells, 2020 Many studies have focused on understanding the regulation and functions of aberrant protein synthesis in colorectal cancer (CRC), leaving the ribosome, its main effector, relatively underappreciated in CRC.
Sophie Nait Slimane +7 more
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