Results 11 to 20 of about 1,557,457 (269)
Mechanistic studies of initiator–initiator interaction and replication initiation [PDF]
The EMBO Journal, 1998 Unlike the chromosome of Escherichia coli that needs only one replication initiator protein (origin recognition protein) called DnaA, many plasmid replicons require dual initiators: host-encoded DnaA and a plasmid-encoded origin recognition protein, which is believed to be the major determinant of replication control. Hitherto, the relative mechanistic
Y B, Lu, H J, Datta, D, Bastia
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The Secrets of Meristems Initiation: Axillary Meristem Initiation and Floral Meristem Initiation
Plants, 2023 The branching phenotype is an extremely important agronomic trait of plants, especially for horticultural crops. It is not only an important yield character of fruit trees, but also an exquisite ornamental trait of landscape trees and flowers. The branching characteristics of plants are determined by the periodic initiation and later development of ...
Qingqing Yang +3 more
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Initial Events in Bacterial Transcription Initiation [PDF]
Biomolecules, 2015 Transcription initiation is a highly regulated step of gene expression. Here, we discuss the series of large conformational changes set in motion by initial specific binding of bacterial RNA polymerase (RNAP) to promoter DNA and their relevance for regulation. Bending and wrapping of the upstream duplex facilitates bending of the downstream duplex into
Emily F. Ruff +2 more
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Memories and history of Hansen's disease in Brazil told by witnesses (1960-2000) [PDF]
História, Ciências, Saúde: Manguinhos, 2003 This report is a preliminary result of a survey on memories and history of Hansen's disease, or 'hanseniasis', prepared by the Fundação Oswaldo Cruz (Fiocruz) and the Universidade Federal do Rio de Janeiro (UFRJ) using statements from those who have been
Laurinda Rosa Maciel +3 more
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Teachers’ perceptions of their own initiative: Collective initiative vs. personal initiative [PDF]
Zbornik Instituta za pedagoska istrazivanja, 2013 Current trends in education demand from teachers to exhibit proactive behaviour and assume responsibility for the implementation of changes in school practice. In that sense, it is important to study how teachers perceive their own initiative and to gain insight into the activities where such initiative is demonstrated.
Džinović, Vladimir +5 more
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Aldehyde Dehydrogenase, a Therapeutic Target in Chordoma: Analysis in 3D Cellular Models
Cells, 2021 Chordomas are rare, slow-growing tumors of the axial skeleton. These tumors are locally aggressive and refractory to conventional therapies. Radical surgery and radiation remain the first-line treatments.
Marie-Anaïs Locquet +13 more
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Nutritional indicators' performance in malnutrition diagnosis of hospitalized elderly patients
Experimental Gerontology, 2023 Background: Several nutritional diagnosis methods and their relationship with clinical outcomes have been described. This study investigated malnutrition in hospitalized elderly patients (HEP) using different nutritional indicators and determined ...
Vânia Aparecida Leandro-Merhi +3 more
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Influence of electronic media on food choices of schoolchildren and adolescents in Luanda, Angola
NAJFNR, 2023 Background: Malnutrition in Angola has reached a prevalence of 17.3 %. On the other hand, the prevalence of childhood obesity is 2.4 %. There has been a food transition in Sub-Saharan Africa, and 28% of consumers obtain their products under the ...
Olineid de Oliveira, Marli Stela Santana
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A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis
Cell Reports, 2016 Melanoma is one of the most lethal cutaneous malignancies, characterized by chemoresistance and a striking propensity to metastasize. The transcription factor ATF2 elicits oncogenic activities in melanoma, and its inhibition attenuates melanoma ...
Giuseppina Claps +15 more
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Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer
Frontiers in Endocrinology, 2017 Oncogenic mutations, such as Ras mutations, drive not only enhanced proliferation but also the metabolic adaptations that confer to cancer cells the ability to sustain cell growth in a harsh tumor microenvironment.
Maria Victoria Recouvreux +1 more
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