Results 61 to 70 of about 3,819,967 (357)
Single molecule studies on the dynamics of the transcription initiation complex of yeast mitochondria [PDF]
, 2017 Department of Biomedical EngineeringThe transcription initiation complex in the yeast mitochondria of Saccharomyces cerevisiae comprises the RNA polymerase, Rpo41, the initiation factor, Mtf1, and the DNA including 6 base pair promoter sequence. The Mtf1
Cho, Hayoon
core
The mammalian ULK1 complex and autophagy initiation
Essays in Biochemistry, 2017 Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the cell.
Maria Zachari, I. Ganley
semanticscholar +1 more source
The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
International Journal of Molecular Sciences, 2020 Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily caused by trauma induced by an external force or by age-related cartilage damage.
Yeri Alice Rim, Yoojun Nam, J. Ju
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Religions, 2020 This essay will explore the challenges presented by transgressive rituals, particularly the secret and wisdom-consort consecrations found in the Mahāyoga and Yoginī tantras.
David B. Gray
doaj +1 more source
The pathway of hepatitis C virus mRNA recruitment to the human ribosome. [PDF]
, 2009 Eukaryotic protein synthesis begins with mRNA positioning in the ribosomal decoding channel in a process typically controlled by translation-initiation factors.
Doudna, Jennifer A +2 more
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Education and the Human Good [PDF]
, 2011 What kind of reasons can be given for believing education is valuable? One can regard education as initiation into practices and refer to the goods internal to practices, but this does not objectively anchor claims about the goodness of education.
Curren, Randall
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Schizophrenia long-acting antipsychotics initiation index (SLAAII)
European Psychiatry, 2021 Introduction Background In individuals with schizophrenia, long-acting injectable antipsychotics (LAIs) have been shown to be beneficial in preventing relapse.
P. Ifteni, A. Teodorescu
doaj +1 more source
Evolving force balance during incipient subduction [PDF]
, 2004 Nearly half of all active subduction zones initiated during the Cenozoic. All subduction zones associated with active back arc extension have initiated since the Eocene, hinting that back arc extension may be intimately associated with an interval ...
Gurnis, Michael, Hall, Chad, Lavier, Luc
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Metabolic pathways regulating colorectal cancer initiation and progression.
Seminars in Cell and Developmental Biology, 2020 Colorectal cancer (CRC) is one of the most common types of cancer worldwide. Despite recent advances in the molecular genetics of CRC, poor treatment outcomes highlight the need for a better understanding of the underlying mechanisms accounting for tumor
Sofia La Vecchia, C. Sebastián
semanticscholar +1 more source