Results 41 to 50 of about 3,031,333 (292)
Initial Events in Bacterial Transcription Initiation [PDF]
Biomolecules, 2015 Transcription initiation is a highly regulated step of gene expression. Here, we discuss the series of large conformational changes set in motion by initial specific binding of bacterial RNA polymerase (RNAP) to promoter DNA and their relevance for regulation. Bending and wrapping of the upstream duplex facilitates bending of the downstream duplex into
Emily F. Ruff +2 more
openaire +3 more sources
Growing Greener Initiative [PDF]
, 2003 Using funds from this grant, the City of Dover Open Lands Committee worked in conjunction with the Planning Department and Conservation Commission to plan, promote and present a series of workshops.
City of Dover, NH
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
The 5I Formula for Successful Staffing of Scientific and Research Organizations
Marketing of Scientific and Research Organizations, 2018 Scientists and engineers create the scientific and technological knowledge to generate societal and individual wealth and related economic growth.
Zehner William Bradley +1 more
doaj +1 more source
Core Support Initiative Evaluation [PDF]
, 2006 In 2004-05, the Blue Shield of California Foundation (BSCF) provided over $10 million in core support funding to 175 community health clinics, clinic parent corporations, and clinic consortia/networks through its Core Support Initiative.
Caroline Krauskopf, Kris Putnam-Walkerly
core
Evaluation of the Fighting Back Initiative [PDF]
, 2005 This case study describes an evaluation of a large-scale, multi-site effort to harness community-generated strategies to reduce the use and abuse of alcohol and illegal drugs.
Kay E. Sherwood
core +1 more source
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson +20 more
wiley +1 more source
VertigO, 2014 With the increasing land challenge, the small farmers have evil to form part of the process of development. In Niger, the land insecurity is without one of the difficulties which limit the agricultural investment.
Sitou Lawali +2 more
doaj +1 more source
Teachers’ perceptions of their own initiative: Collective initiative vs. personal initiative [PDF]
Zbornik Instituta za pedagoska istrazivanja, 2013 Current trends in education demand from teachers to exhibit proactive behaviour and assume responsibility for the implementation of changes in school practice. In that sense, it is important to study how teachers perceive their own initiative and to gain insight into the activities where such initiative is demonstrated.
Džinović, Vladimir +5 more
openaire +2 more sources