Results 71 to 80 of about 1,329,071 (310)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
, 1996 [Main report] -- Executive summary -- attachment I. Management measures, books 1-4 -- attachment II. Science Team information and products -- attachment III. Information related to habitat restoration projects -- attachment IV.
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Autonomie, responsabilité et coopération : ce qu’en disent les élèves utilisant un plan de travail
Éducation et Socialisation, 2016 The educational tool « work plan », introduced by Helen Parkhurst at the beginning of the twentieth century, is a document in which each student can find learning activities within his or her reach.
Sylvain Connac
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Academic literacy program implementation in an Ecuadorian University: a multinomial logit approach
International Journal of Adolescence and Youth, 2019 The ‘FCSHlee’ program proposed by ESPOL Polytechnic University’s School of Social and Humanistic Sciences (FCSH, acronym in Spanish), consisted in the implementation of a reading requirement of culturally enriching book by subject.
Silvia Mariela Méndez Prado +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Die Initiative "Medienbildung JETZT!"
Medienimpulse, 2017 Die Initiative "Medienbildung JETZT!" wurde 2011 als community of practice ins Leben gerufen, um die Vernetzung all jener zu fördern, die im Bereich der Medienbildung tätig sind, und ihre Anliegen zu vertreten.
Christoph Kaindel
doaj +1 more source