Results 221 to 230 of about 31,868 (277)

Advancements in Injectable Hydrogels for Controlled Insulin Delivery: A Comprehensive Review of the Design, Properties and Therapeutic Applications for Diabetes and Its Complications. [PDF]

Polymers (Basel)
Li L, Wang Y.
europepmc   +1 more source

Multi‐scale Engineered Vasculature and Hierarchical Porosity via Volumetric Bioprinting‐Guided Photopolymerization‐Induced Phase Separation

Advanced Materials, EarlyView.
Vascularization in bioprinted hydrogels is limited by nanoscale porosity in hydrogel bionks. Volumetric bioprinting of gelatin–norbornene phase‐separating hydrogels permits to create centimeter‐scale constructs featuring interconnected multi‐scale porosity. Light dose gradients result in spatially controlled pore dimensions. Capillary‐scale vessels are
Oksana Y. Dudaryeva, Maj‐Britt Buchholz, Gabriel Größbacher, Sofia Amaral, Sammy Florczak, Camille Bonhomme, Alvaro Rojo Ferrer, Mark W. Tibbitt, Riccardo Levato   +8 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration. [PDF]

Mater Today Bio
Agarwal G, Moes K, Schmidt CE.
europepmc   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Decellularised extracellular matrix-based injectable hydrogels for tissue engineering applications. [PDF]

Biomater Transl
Guo WY, Wang WH, Xu PY, Kankala RK, Chen AZ.   +4 more
europepmc   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Harnessing hydrogen sulfide in injectable hydrogels that guide the immune response and osteoclastogenesis balance for osteoporosis treatment. [PDF]

Mater Today Bio
Jiang L, Wu Y, Xu Z, Hou M, Chen S, Cheng C, Hu D, Lu D, Zhu X, Li C.   +9 more
europepmc   +1 more source

Development of Artificial Sebaceous Gland‐Integrated In Vitro Human Skin Model

Advanced Materials Interfaces, EarlyView.
Uniform 3D artificial sebaceous gland spheroids, termed SebaSpheres, are generated at high throughput using a microfluidic platform and structurally integrated into a collagen‐based skin construct containing fibroblasts and keratinocytes. This work presents a modular and scalable fabrication and integration strategy for incorporating sebaceous gland ...
Daeun Ryu, Hyewon Noh, Jimin Son, Haejung Lee, Bo Mi Kang, Chong Won Choi, Jong Hwan Sung, Jae Jung Kim   +7 more
wiley   +1 more source

Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment. [PDF]

J Nanobiotechnology
Zhu Y, Xiu Z, Jiang X, Zhang H, Li X, Feng Y, Li B, Cai R, Li C, Tao G.   +9 more
europepmc   +1 more source