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Rapid Photocrosslinkable Thermoresponsive Injectable Polyphosphazene Hydrogels
Macromolecular Rapid Communications, 2010AbstractRapidly photocrosslinkable and thermosensitive polyphosphazene polymers have been prepared to overcome the limitations associated with long UV exposure. Short UV exposure on the thermosensitive gels under mild conditions leads to quick photocrosslinking of the acrylate groups in the polymer network, and results in a dual crosslinked network ...
Thrimoorthy, Potta +2 more
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Injectable hydrogels for delivering biotherapeutic molecules
International Journal of Biological Macromolecules, 2018To date, numerous delivery systems based on either organic or inorganic material have been developed to achieve efficient and sustained delivery of therapeutics. Hydrogels, which are three dimensional networks of crosslinked hydrophilic polymers, have a significant role in solving the clinical and pharmacological limitations of present systems because ...
Ansuja Pulickal, Mathew +4 more
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Injectable Hydrogels from Segmented PEG-Bisurea Copolymers
Biomacromolecules, 2012We describe the preparation of an injectable, biocompatible, and elastic segmented copolymer hydrogel for biomedical applications, with segmented hydrophobic bisurea hard segments and hydrophilic PEG segments. The segmented copolymers were obtained by the step growth polymerization of amino-terminated PEG and aliphatic diisocyanate.
Pawar, G.M. +6 more
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Injectable Intraocular Lens Materials Based upon Hydrogels
Biomacromolecules, 2001The possibilities to develop an injectable hydrogel lens were investigated. Aqueous solutions of reactive polymers in combination with a water-soluble blue light photoinitiator were transformed into hydrogels by irradiation with blue light. Poly(ethylene glycol) diacrylates (PEGDA) with low molecular weights and an acrylate modified copolymer of N ...
de Groot, JH +6 more
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Injectable intraocular lens using hydrogels
Journal of Drug Delivery Science and Technology, 2007Presbyopia is an age-related condition that begins to develop in humans around the age of forty, resulting in anatomical and physiological changes in the choroids, ciliary body, vitreous, lens capsule, and lens fibers. A suitable biomaterial is needed for the implantation of intraocular lenses (IOL) that could be used to treat the symptoms of ...
M.K. Yoo +4 more
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Injectable Hydrogels for 3D Bioprinting
2021Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug ...
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Polysaccharide-based Injectable Smart Hydrogels
Polysaccharides, being the most widely available and naturally occurring macromolecular polymer groups, represent a sustainable source for development of advanced hydrogel technologies. This chapter examines the status and future directions of injectable polysaccharide-based hydrogels and the role in which smart functions may contribute to the ...O. M. Clarkin, S. A. Brady
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