Tunable biohybrid hydrogels from coacervation of hyaluronic acid and PEO‐based block copolymers [PDF]
, 2020 Accurately tuning the macroscopic properties of biopolymer‐based hydrogels remains challenging due to the ill‐defined molecular architecture of the natural building blocks.
Gopez, Jeffrey D. +3 more
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Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
Gels, 2023 Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment.
Hossein Omidian, Sumana Dey Chowdhury
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Chitosan based injectable hydrogels for smart drug delivery applications
Sensors International, 2022 Hydrogels have a number of characteristics that make them an ideal candidate for biomedical applications. Chitosan is a well-known natural polymer, and it is favoured due to its good biocompatibility, low toxicity, and biodegradability characteristics ...
Ishita Singha, Aalok Basu
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Enzymatic Cross-Linking of Dynamic Thiol-Norbornene Click Hydrogels [PDF]
, 2019 Enzyme-mediated in situ forming hydrogels are attractive for many biomedical applications because gelation afforded by enzymatic reactions can be readily controlled not only by tuning macromer compositions, but also by adjusting enzyme kinetics.
Hudson, Britney N. +3 more
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Stimulus-responsive Injectable Polysaccharide Scaffolds for Soft Tissue Engineering Prepared by O/W High Internal Phase Emulsion [PDF]
, 2011 This thesis describes work on the development of several novel stimuli-responsive porous hydrogels prepared from oil-in-water (o/w) high internal phase emulsion (HIPE) as injectable scaffolds for soft tissue engineering.
Zhou, Shengzhong, Zhou, Shengzhong
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Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]
, 2013 Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa +8 more
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Vortex-Induced Injectable Silk Fibroin Hydrogels [PDF]
Biophysical Journal, 2009 A novel, to our knowledge, technique was developed to control the rate of beta-sheet formation and resulting hydrogelation kinetics of aqueous, native silk solutions. Circular dichroism spectroscopy indicated that vortexing aqueous solutions of silkworm silk lead to a transition from an overall protein structure that is initially rich in random coil to
Yucel, Tuna +2 more
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Chemical signal regulated injectable coacervate hydrogels
Chemical Science, 2023 Incorporation of reversible Michael addition controlled coacervate crosslinks in a polymer hydrogel led to injectable gels that are responsive to nucleophilic chemical signals, enabling accelerated degradation in culture media after injection.
Bohang Wu +9 more
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Injectable Hydrogel-Based Nanocomposites for Cardiovascular Diseases
Frontiers in Bioengineering and Biotechnology, 2020 Cardiovascular diseases (CVDs), including a series of pathological disorders, severely affect millions of people all over the world. To address this issue, several potential therapies have been developed for treating CVDs, including injectable hydrogels ...
Xiaoshan Liao +8 more
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Injectable Hydrogels: A Review of Injectability Mechanisms and Biomedical Applications
Research in Molecular Medicine, 2018 Hydrogels have been used for biomedical applications in recent decades. They are a perfect candidate for regenerative medicine as they resemble the extracellular matrix of native tissues. In addition, their highly hydrated structure makes them a suitable
Amir Mellati, Javad Akhtari
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