Results 41 to 50 of about 15,949,907 (242)

The injection of methadone syrup in New South Wales: patterns of use and increased harm after partial banning of injecting equipment

Australian and New Zealand Journal of Public Health, 2003
Objective: To describe methadone injectors and the risk practices associated with injecting methadone in New South Wales, Australia. To assess the impact on injecting drug use and risk behaviour of the withdrawal of methadone injecting equipment from ...
Max Hopwood, Erica Southgate, Susan Kippax, Gabriele Bammer, Geetha Isaac‐Toua, Margaret MacDonald   +5 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Injecting drugs alone during an overdose crisis in Vancouver, Canada

Harm Reduction Journal, 2022
Background Settings throughout Canada and the USA continue to experience crises of overdose death due to the toxic unregulated drug supply. Injecting drugs alone limits the potential for intervention and has accounted for a significant proportion of ...
Alexa Norton, Kanna Hayashi, Cheyenne Johnson, JinCheol Choi, M-J Milloy, Thomas Kerr   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Estimating prevalence of injecting drug users and associated heroin-related death rates in England by using regional data and incorporating prior information [PDF]

, 2013
Injecting drug users (IDUs) have a direct social and economic effect yet can typically be regarded as a hidden population within a community. We estimate the size of the IDU population across the nine different Government Office regions of England in ...
Ruth King, Bird, Sheila, Overstall, Antony M., Bird, Sheila M, Hutchinson, Sharon, Sheila M. Bird, Sharon J. Hutchinson, Hutchinson, Sharon; id_orcid, Hutchinson, Sharon J., Overstall, Antony, Antony M. Overstall, King, Ruth, Hay, Gordon, Gordon Hay   +13 more
core   +2 more sources

Examination of the risk of reinfection with hepatitis C among injecting drug users who have been tested in Glasgow [PDF]

, 2012
Unsafe injecting practices put injecting drug users (IDUs) at repeat exposure to infection with the hepatitis C virus (HCV). It has not yet been determined if spontaneously clearing one's primary infection influences the risk of reinfection; our aim was ...
Hutchinson, Sharon, Goldberg, David J., Cameron, S.O., Innes, Hamish, McLeod, Allan, Mcdonald, Scott   +5 more
core   +4 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Estimating prevalence of injecting drug users and associated heroin-related death rates in England by using regional data and incorporating prior information [PDF]

, 2014
Injecting drug users (IDUs) have a direct social and economical impact, yet can typically be regarded as a hidden population within a community. We estimate the size of the IDU population across the nine different Government Office Regions of England in ...
Hutchinson, Sharon J., King, Ruth, Overstall, Antony M., Hay, Gordon, Bird, Sheila M   +4 more
core   +2 more sources

Addressing injecting related risks among people who inject both opioids and stimulants: Findings from an Australian survey of people who inject drugs

Addictive Behaviors Reports, 2022
Background: Opioids and stimulants are the most commonly injected illicit drugs worldwide and in Australia. While some people who inject drugs (PWID) prefer either opioids or stimulants, others regularly use both opioids and stimulants. Limited available
L. Brener, T. Caruana, T. Broady, E. Cama, N. Ezard, A. Madden, C. Treloar   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source