Results 61 to 70 of about 91,513 (309)

Stigmatization of people who inject drugs (PWID) by pharmacists in Tajikistan: sociocultural context and implications for a pharmacy-based prevention approach

Harm Reduction Journal, 2017
Background Pharmacies are an important source of sterile syringes for people who inject drugs (PWID) in Tajikistan who are under high risk of HIV and hepatitis C virus.
Umedjon Ibragimov, Hannah L. Cooper, Regine Haardörfer, Kristin L. Dunkle, William A. Zule, Frank Y. Wong   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Risky Behaviors of Injecting Drug Users (IDUs) Referred to Addiction Rehabilitation Centers in Khuzestan Province in 2014

Online Journal of Health & Allied Sciences, 2017
Aim: In the last decade, the prevalence of injecting drugs has been increasing rapidly. Injecting drug use puts one at the risk of risky behaviors that affect the health of individual and society.
Farkhondeh Jamshidi, Iraj Nazari, Maria Cheraghi   +2 more
doaj  

Imprisonment, injecting drug use, and bloodborne viruses [PDF]

BMJ, 1995
The possibility that imprisonment is a risk factor for HIV transmission has been much debated, even though the association between imprisonment, use of injecting drugs, and the transmission of another bloodborne virus, hepatitis B, was recognised more than 20 years ago.1 In the past five years, clusters of cases of acute hepatitis B infection ...
O N, Gill, A, Noone, J, Heptonstall
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The Experience of Safety, Harassment and Social Exclusion Among Male Clients of Sydney’s Medically Supervised Injecting Centre

International Journal for Crime, Justice and Social Democracy, 2022
Research on drug harm reduction services has found these operate as a safe haven from health harm. Less is known about the wider sense of security experienced by clients of such services as a counterbalance to social marginality in their daily lives.
George Dertadian, Stephen Tomsen
doaj   +1 more source

Potential geographic "hotspots" for drug-injection related transmission of HIV and HCV and for initiation into injecting drug use in New York City, 2011-2015, with implications for the current opioid epidemic in the US.

PLoS ONE, 2018
ObjectiveWe identified potential geographic "hotspots" for drug-injecting transmission of HIV and hepatitis C virus (HCV) among persons who inject drugs (PWID) in New York City.
D C Des Jarlais, H L F Cooper, K Arasteh, J Feelemyer, C McKnight, Z Ross   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Social structural factors that shape assisted injecting practices among injection drug users in Vancouver, Canada: a qualitative study

Harm Reduction Journal, 2010
Background Injection drug users (IDU) commonly seek manual assistance with illicit drug injections, a practice known to be associated with various health-related harms.
Fairbairn Nadia, Small Will, Van Borek Natasha, Wood Evan, Kerr Thomas   +4 more
doaj   +1 more source