Results 41 to 50 of about 3,571,375 (291)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

HCV non-1b genotypes in injecting drug users from Romania

Journal of Infection in Developing Countries, 2016
Introduction: Chronic hepatitis C cases diagnosed in Romania were mostly related to unsafe parenteral treatments and blood transfusions; HCV genotype 1b was prevalent.
Simona Ruta, Camelia Sultana, Cristiana Oprea, Codruta Vagu, Emanoil Ceausu, Costin Cernescu   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Estimating prevalence of injecting drug users and associated heroin-related death rates in England by using regional data and incorporating prior information [PDF]

, 2013
Injecting drug users (IDUs) have a direct social and economic effect yet can typically be regarded as a hidden population within a community. We estimate the size of the IDU population across the nine different Government Office regions of England in ...
Ruth King, Bird, Sheila, Overstall, Antony M., Bird, Sheila M, Hutchinson, Sharon, Sheila M. Bird, Sharon J. Hutchinson, Hutchinson, Sharon; id_orcid, Hutchinson, Sharon J., Overstall, Antony, Antony M. Overstall, King, Ruth, Hay, Gordon, Gordon Hay   +13 more
core   +2 more sources

Hepatitis C testing and status among opioid substitution treatment clients in New South Wales

Australian and New Zealand Journal of Public Health, 2014
Background: In Australia about half of the people who inject drugs (PWID) are hepatitis C (HCV) antibody positive (anti‐HCV+). The prevalence among opioid substitution treatment (OST) clients specifically is unclear, despite OST clinics being a potential
Fiona L. Shand, Carolyn Day, William Rawlinson, Louisa Degenhardt, Nicholas G. Martin, Elliot C. Nelson   +5 more
doaj   +1 more source

Encephalitis of the Basal Ganglia in an Injection Drug User [PDF]

Clinical Infectious Diseases, 2007
A 24-year-old white female intravenous heroin user with osteogenesis imperfecta presented with a 3-day history of diminished level of consciousness. On physical examination, she was febrile to 39.1?C, tachycardic (pulse rate, 120 beats per minute), and had a blood pressure of 100/55 mm Hg.
P. A. Mackowiak, M. Carpenter, C. Polk, R. Castellani, K. Mochoruk, S. Sanche, B. Stern, M. S. Donnenberg   +7 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Did Inclusion of informed consent affect the observed hiv prevalence rate among injecting drug users during hiv sentinel surveillance 2017 in Delhi, Uttar Pradesh, Uttarakhand, and Jharkhand States of Central Zone of India?

Indian Journal of Public Health, 2020
Background: In 2017, the sampling procedure for HIV sentinel surveillance (HSS) among all high-risk groups was changed from the consecutive sampling to random sampling along with the introduction of linked anonymous testing strategy with informed written
Sanjay Kumar Rai, Farhad Ahamed, Shashi Kant, Partha Haldar, Shreya Jha, Shobini Rajan   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The syringe gap: an assessment of sterile syringe need and acquisition among syringe exchange program participants in New York City

Harm Reduction Journal, 2009
Background Programmatic data from New York City syringe exchange programs suggest that many clients visit the programs infrequently and take few syringes per transaction, while separate survey data from individuals using these programs indicate that ...
Siegler Anne, Paone Denise, Heller Daliah I, Karpati Adam   +3 more
doaj   +1 more source