Results 181 to 190 of about 17,021,466 (309)

Cognitive function and mortality among persons aging with HIV and injection drug use. [PDF]

AIDS
Piggott DA, Mehta SH, Rubin LH, Sun J, Leng SX, Kirk GD.   +5 more
europepmc   +1 more source

COVID-19 vaccine effectiveness by HIV status and history of injection drug use: a test-negative analysis. [PDF]

J Int AIDS Soc, 2023
Puyat JH, Wilton J, Fowokan A, Janjua NZ, Wong J, Grennan T, Chambers C, Kroch A, Costiniuk CT, Cooper CL, Lauscher D, Strong M, Burchell AN, Anis A, Samji H, COVAXHIV Study Team.   +15 more
europepmc   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Correction to: Burden of Injection Drug Use-Related Infection Hospitalizations in Tennessee, 2016-2023. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

A Single-Centre Canadian Cost Analysis for the Care and Management of Injection Drug Use-Associated Infective Endocarditis Requiring Cardiac Surgery. [PDF]

CJC Open
Brown AN, Stevens K, Kim T, Hemmati S, Koury H, Sandhu J, Harten C, Sembo TWS, Kent WDT, Adams C, Hassanabad AF.   +10 more
europepmc   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Injection Drug Use and Sexual Behaviors Associated With Infection Transmission and Access to Harm Reduction for People Who Use Drugs and Sell Sex in the Rural US. [PDF]

Subst Use
Mixson LS, Young AM, Tsui JI, Jenkins WD, Pho MT, Seal DW, Drumright LN, Ruderman SA, Stopka TJ, Korthuis PT, Whitney BM, Friedmann PD, Westergaard RP, Go VF, Miller WC, Khoury D, Feinberg J, Smith G, Cooper HLF, Delaney JA, Crane HM.   +20 more
europepmc   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Neurocognitive Impairment in ART-Experienced People Living with HIV: An Analysis of Clinical Risk Factors, Injection Drug Use, and the sCD163. [PDF]

Viruses
Ahmed SZ, Amin F, Farooqui N, Omarova Z, Mahmood SF, Khan QUA, Naqvi HA, Mumtaz A, Baig S, Khan MR, Shah SA, Hassan A, Bolla S, Mushtaq S, Abidi SH.   +14 more
europepmc   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source