Results 51 to 60 of about 17,021,466 (309)

Syringe exchange, injecting and intranasal drug use [PDF]

Addiction, 2009
ABSTRACTObjective  To assess trends in injecting and non‐injecting drug use after implementation of large‐scale syringe exchange in New York City. The belief that implementation of syringe exchange will lead to increased drug injecting has been a persistent argument against syringe exchange.Methods  Administrative data on route of administration for ...
Don C, Des Jarlais, Kamyar, Arasteh, Courtney, McKnight, Martin, Ringer, Samuel R, Friedman   +4 more
openaire   +2 more sources

Regional differences in HIV prevalence among drug users in China: potential for future spread of HIV? [PDF]

, 2008
Kretzschmar M, Zhang W, Mikolajczyk RT, et al. Regional differences in HIV prevalence among drug users in China: potential for future spread of HIV? BMC Infectious Diseases. 2008;8(1):108.Background: Drug use and in particular injecting drug use has been
Weidong Zhang, Wang, Lan, Lv Fan, Lv, Fan, Xinhua Sun, Zhang Weidong, Sun, Xinhua, Alexander Kraemer, Fan Lv, Kretzschmar, Mirjam, Wang Lan, Sun Xinhua, Mirjam Kretzschmar, Kretzschmar Mirjam, Kraemer Alexander, Zhang, Weidong, Krämer, Alexander ; https://orcid.org/, Mikolajczyk Rafael T, Mikolajczyk, Rafael T., Lan Wang, Rafael T Mikolajczyk   +20 more
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Wound Botulism in Injection Drug Users: Time to Antitoxin Correlates with Intensive Care Unit Length of Stay

Western Journal of Emergency Medicine, 2009
Objectives: We sought to identify factors associated with need for mechanical ventilation (MV), length of intensive care unit (ICU) stay, length of hospital stay, and poor outcome in injection drug users (IDUs) with wound botulism (WB).Methods: This is a
Offerman, Steven R, Schaefer, Melissa, Thundiyil, Joseph, Cook, Matthew D, Holmes, James F   +4 more
doaj  

A qualitative study of persons who inject drugs but who have never helped others with first injections: how their views on helping contrast with the views of persons who have helped with first injections, and implications for interventions

Harm Reduction Journal, 2018
Background Transitioning from non-injection to injection drug use dramatically escalates health risks. Evidence suggests that people who inject drugs (PWID) help in a majority of others’ first injections, yet these helpers represent only a minority of ...
David M. Barnes, Don C. Des Jarlais, Margaret Wolff, Jonathan Feelemyer, Susan Tross   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Yeast fungaemia among injection drug users in France (2012–2022): a cross-sectional observational studyResearch in context

The Lancet Regional Health. Europe
Summary: Background: Intravenous injection drug use (IVDU) is an established but infrequent risk factor for yeast fungaemia. We aimed to identify features and outcomes of yeast fungaemia associated with IVDU in a nationwide surveillance network in ...
Olivier Paccoud, Olivier Lortholary, Sebastien Imbert, Valerie Letscher-Bru, Karine Boukris-Sitbon, Thomas Obadia, Frederic Dalle, Lilia Hasseine, Florent Morio, Antoine Huguenin, Philippe Poirier, Loic Favennec, Julie Bonhomme, Alexandre Alanio, Fanny Lanternier, Marie Desnos-Ollivier, Taieb Chouaki, Marc Pihet, Anne-Pauline Bellanger, Magalie Demar, Nicole Desbois-Nogard, Muriel Nicolas, Marie-Fleur Durieux, Milène Sasso, Estelle Perraud-Cateau, Jean-Pierre Gangneux, Caroline Mahinc, Sophie Cassaing, Adelaide Chesnay, Guillaume Desoubeaux, André Paugam, Elisabeth Chachaty, Marie-Elisabteth Bougnoux, Lilia Merabet, Patricia Mariani, Maité Micaelo   +35 more
doaj   +1 more source

Transition from First Drug Use to Regular Injection among People Who Inject Drugs in Iran [PDF]

Addiction and Health, 2018
Background: The study aimed to evaluate the interval between first drug use and regular injection and factors associated with transition from first injection into premature regular injection among people who inject drugs (PWIDs).Methods: In a multicenter
Masoomeh Koozegar, Armita Shahesmaeili, Mehdi Noroozi   +2 more
doaj  

Designing an experimental HIV/HCV intervention to promote the safe re-use of drug preparation materials by injection drug users in Puerto Rico

Harm Reduction Journal, 2008
Injection drug users (IDUs) in San Juan, Puerto Rico are characterized by high rates of daily injecting, injection of shared drugs, re-use of injection syringes, and use of shooting galleries.
Robles Rafaela R, Negrón Juan, Colón Héctor M, Finlinson H Ann   +3 more
doaj   +1 more source

Epidemiology of Injection Drug Use [PDF]

The Canadian Journal of Psychiatry, 2016
After more than 30 years of research, numerous studies have shown that injection drug use is associated with a wide range of adverse health outcomes such as drug overdoses, drug-related suicidal behaviours, comorbid psychiatric disorders, bloodborne pathogens and other infectious diseases, and traumas.
Élise, Roy, Nelson, Arruda, Julie, Bruneau, Didier, Jutras-Aswad   +3 more
openaire   +2 more sources