Results 121 to 130 of about 6,150,128 (285)
Sandwich injection moulding with thermoset materials [PDF]
This project aimed to study the feasibility of making a thermoset sandwich injection moulding from a novel thermoset co-injection moulding system. Two thermoset polyesters, BMC and a powder coating, were used for all experiments.
Kiatmanaroj, Subongkoj
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Phase-stabilised self-injection-locked microcomb
Microresonator frequency combs (microcombs) hold potential for precision metrology in a compact form factor impacting applications such as point-of-care diagnostics, environmental monitoring, time-keeping, navigation and astronomy.
Tobias Herr (9402692) +4 more
core +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
电力工程技术The impact of electromagnetic interference on secondary systems in substations can be reduced by the installation of secondary equipotential grounding grid.
Zhiwei CAO +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Central Point Notice of Adopted Amendment (2008-05-19)
, 2008 14 pp. Adopted 2008-05-19. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached approved amendment is the updated population and demographic element of the City of Central Point Comprehensive Plan.
Central Point (Or.)
core +1 more source