Results 81 to 90 of about 812,736 (249)

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Safety of Intra-articular Corticosteroid Injection [PDF]

Radiology, 2020
Matthew Jiang, Keith Lim, Mandana Nikpour   +2 more
openaire   +5 more sources

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

Assessing the Effectiveness of Ultrasound-Guided injections of Steroid for Knee Osteoarthritis on Three Different Sites: A Randomized Controlled Trial

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College
Objective: The aim of this study was to explore the impact of ultrasound-guided injections at various sites at the knee joint. Method: One hundred and twenty subjects with grade III and IV knee OA were enrolled in the study.
Ashfaque Hussain Mir, Imran Ahmed, Raheel Akbar Baloch, Aamir Usman Memon, Moazna Talpur, sadia kazi   +5 more
doaj   +3 more sources

Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone

, 2015
Cesáreo Ángel Trueba Davalillo,1,2 Cesáreo Trueba Vasavilbaso,2 José Mario Navarrete Álvarez,2 Pilar Coronel Granado,3 Ozcar Alejandro García Jiménez,2 Mercedes Gimeno del Sol,3 Félix Gil Orbezo2 ...
Trueba Davalillo CA, Gil Orbezo F, Gimeno del Sol M, Coronel Granado P, García Jiménez OA, Navarrete Álvarez JM, Trueba Vasavilbaso C   +6 more
core  

The efficacy of intra-articular PRP, ozone and ozone+PRP injections in patients with osteoarthritis [PDF]

, 2018
Osteoarthritis (OA) is the most common form of arthritis and some joints are effected more than others. The prevalence of OA increases with age and it represents the major problem for functional impairment in older patients.
Ellialtioglu, Aysegul, Baeza Noci, José, Yeprem, Lale   +2 more
core   +1 more source

Lateral and Anterior Closing Wedge “9/9” Degree Osteotomy to Correct Both Tibia Vara and Excessive Tibial Slope

Arthroscopy Techniques, EarlyView.
Abstract High tibial osteotomy is a key option for patients with unicompartmental overload or instability. Although coronal correction for varus deformity is well established, excessive posterior tibial slope (PTS) is increasingly recognized as a contributor to anterior cruciate ligament graft failure.
Julien Druel, Antoine Piercecchi, Chris Wilson, Maher Ghandour, Kristian Kley, Matthieu Ollivier   +5 more
wiley   +1 more source

The use of platelet rich plasma in the treatment of degenerative joint disease in cats: an exploratory case series

Frontiers in Veterinary Science
ObjectiveTo evaluate the effectiveness of intra-articular autologous Platelet Rich Plasma (PRP) in managing Degenerative Joint Disease (DJD) in cats.DesignProspective pilot clinical trial.MethodsSix domestic cats with clinically and radiographically ...
Janice Huntingford, Andrea Looney, James Johnson, Lisa Miller   +3 more
doaj   +1 more source

Cutibacterium acnes Septic Arthritis of the Nonoperated Knee: A Case Report

The Surgery Journal, 2017
Cutibacterium (Propionibacterium) acnes, a gram-positive bacillus with low pathogenicity, is an uncommon but known cause of prosthetic joint infections, particularly related to shoulder surgery. C.
Kelechi R. Okoroha, Michael D. Gabbard II, Jamal Fitts, Trevor R. Banka   +3 more
doaj   +1 more source