Results 81 to 90 of about 26,232 (250)

Pharmacology of intra-articular triamcinolone

, 2014
Introduction: The inflammatory joint diseases of juvenile inflammatory arthritis (JIA), rheumatoid arthritis (RA) and osteoarthritis (OA): and also mild to moderate joint injury, all require a multidisciplinary approach to management.
Kean, W F, Scherer, J, Kean, C A, Rainsford, Kim   +3 more
core   +1 more source

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone

, 2015
Cesáreo Ángel Trueba Davalillo,1,2 Cesáreo Trueba Vasavilbaso,2 José Mario Navarrete Álvarez,2 Pilar Coronel Granado,3 Ozcar Alejandro García Jiménez,2 Mercedes Gimeno del Sol,3 Félix Gil Orbezo2 ...
Trueba Davalillo CA, Gil Orbezo F, Gimeno del Sol M, Coronel Granado P, García Jiménez OA, Navarrete Álvarez JM, Trueba Vasavilbaso C   +6 more
core  

Intra-articular facet joint injections for low back pain : a systematic review [PDF]

, 2016
Purpose: Evidence supporting the use of therapeutic intra-articular facet joint injections for patients with suspected facet joint pain is sparse. A systematic review including a narrative synthesis was carried out to determine if intra-articular facet ...
Nicholas Henschke, Underwood, Martin, David R. Ellard, Sandhu, Harbinder, Martin Underwood, Ree’thee Bhatt, Bhatt, Ree’thee, Rajni Vekaria, Vekaria, Rajni, Henschke, Nicholas, Ellard, David R., Harbinder Sandhu   +11 more
core   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

Arthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid, Samuel Kemble, Oladimeji Abudu, Anella Saviano, Christopher Mahony, Jonathan W. Lewis, Thomas A. Nicholson, Anna Schettino, Noemi Marigliano, Kathryn Frost, Jenefa Begum, Alyssa M. Urbanowski, Marion Limo, Rakesh Jha, Sandra Martinez Jarquin, Laleh Pezhman, Abbie E. A. Degan, Amy E. Anderson, Charlotte G. Smith, Armaiti Batki, Holly Adams, Francesco Caso, Raffaele Scarpa, Iain McInnes, Stefan Siebert, Arthur G. Pratt, Andrew Filer, Karim Raza, Adam P. Croft, Myriam Chimen, Felicity de Cogan, G. Ed Rainger, Asif J. Iqbal, Francesco Maione, Helen M. McGettrick   +34 more
wiley   +1 more source

Intra-articular hyaluronic acid injections for hip osteoarthritis: a level I systematic review

Purpose: The present systematic review investigated the efficacy of intra-articular hyaluronic acid (HA) viscosupplementation for hip osteoarthritis (OA) in patient-reported outcome measures (PROMs) and whether different molecular weights of HA are ...
Maffulli, Nicola, Katusic, Dragana, Migliorini, Filippo, Mazzoleni, Manuel Giovanni, Pilone, Marco, Schäfer, Luise   +5 more
core   +1 more source

Synovial fluid detection in intra-articular injections using a bioimpedance probe (BIP) needle-a clinical study [PDF]

, 2017
Intra-articular glucocorticoid injections are the recommended treatment for active arthritis, but accurate positioning of the needle may be challenging.
Kari, Juho, Peltomaa, Ritva, Kronstrom, Kai, Kankaanpää, Eeva, Relas, Heikki, Halonen, Sanna, Parmanne, Pinja, Luosujärvi, Riitta   +7 more
core   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

The use of platelet rich plasma in the treatment of degenerative joint disease in cats: an exploratory case series

Frontiers in Veterinary Science
ObjectiveTo evaluate the effectiveness of intra-articular autologous Platelet Rich Plasma (PRP) in managing Degenerative Joint Disease (DJD) in cats.DesignProspective pilot clinical trial.MethodsSix domestic cats with clinically and radiographically ...
Janice Huntingford, Andrea Looney, James Johnson, Lisa Miller   +3 more
doaj   +1 more source

Assessing the Effectiveness of Ultrasound-Guided injections of Steroid for Knee Osteoarthritis on Three Different Sites: A Randomized Controlled Trial

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College
Objective: The aim of this study was to explore the impact of ultrasound-guided injections at various sites at the knee joint. Method: One hundred and twenty subjects with grade III and IV knee OA were enrolled in the study.
Ashfaque Hussain Mir, Imran Ahmed, Raheel Akbar Baloch, Aamir Usman Memon, Moazna Talpur, sadia kazi   +5 more
doaj   +3 more sources