Results 231 to 240 of about 146,863 (270)

Improved Orthogonality in Naphthalimide/Cyanine Dyad Boosts Superoxide Generation: a Tumor‐Targeted Type‐I Photosensitizer for Photodynamic Therapy of Tumor by Inducing Ferroptosis

Advanced Science, EarlyView.
A tumor‐targeted, renal‐metabolized, and less O2‐dependent Type‐I photosensitizer is presented for photodynamic therapy of tumors. The formation of an intramolecular sandwich‐like π–π assembly ensures its rigid orthogonal geometry, thereby improving the superoxide (O2•−)‐generating ability, promoting the intracellular formation of hydroxy radical (HO•),
Guangxiao Yao, Junfeng Miao, Yingying Huo, Wei Guo   +3 more
wiley   +1 more source

Application of a multifunctional chemotherapy infusion device for reducing antineoplastic drug extravasation. [PDF]

Front Oncol
Yang LH, Liu LP, Jiang FY, Huang FZ, Xie CF, Lin XQ, Wang P, Feng XL.   +7 more
europepmc   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

Advanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu, Jingjun He, Haoxuan Ying, Cuiying Chen, Chongyang Zheng, Peng Luo, Weiliang Zhu, Ting Wei, Bufu Tang, Jian Zhang   +9 more
wiley   +1 more source

Risk Factors of Hepatitis B Virus Infection in the Kurdistan Region of Iraq: A Cross-Sectional Study. [PDF]

Mediterr J Hematol Infect Dis
Hussein NR, Abozait HJ, Naqid IA, Ibrahim NM, Khalid FK, Musa DH, Saleem ZS.   +6 more
europepmc   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source

Management of anesthesia for photoimmunotherapy. [PDF]

J Anaesthesiol Clin Pharmacol
Rajan S, Saji N, Bhuyan M, Arul L.
europepmc   +1 more source

Silk Fibroin Nanoparticles for Enhanced Cuproptosis and Immunotherapy in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
Cuproptosis can be triggered via intracellular copper overload mediated by elesclomol (ES).Enhancing ES‐Cu's tumor targeting and circulation stability can efficiently induce tumor cuproptosis. TSF@ES‐Cu protect ES‐Cu, target tumors via natural RGD sequences, and release through multi‐responsiveness.
Si Gao, Haodong Ge, Lili Gao, Ying Gao, Shuibin Tang, Yiming Li, Zhiqing Yuan, Wei Chen   +7 more
wiley   +1 more source

Human umbilical cord mesenchymal stem cells toxicity and allergy effects: In vivo assessment. [PDF]

PLoS One
Cheng WD, Bin L, Lin ZX, Yu D, Xiang DK, Lo S, Ravichandran M, Kong TS.   +7 more
europepmc   +1 more source

Extracellular Vesicles: A Review of Their Therapeutic Potentials, Sources, Biodistribution, and Administration Routes. [PDF]

Int J Nanomedicine
Su X, Wang H, Li Q, Chen Z.
europepmc   +1 more source

Non-Invasive Delivery of CRISPR/Cas9 Ribonucleoproteins (Cas9 RNPs) into Cells via Nanoparticles for Membrane Transport. [PDF]

Pharmaceutics
Tashima T.
europepmc   +1 more source