Results 41 to 50 of about 455,846 (303)

Advantageous Reactivity of Unstable Metal Complexes: Potential Applications of Metal-Based Anticancer Drugs for Intratumoral Injections

Pharmaceutics, 2022
Injections of highly cytotoxic or immunomodulating drugs directly into the inoperable tumor is a procedure that is increasingly applied in the clinic and uses established Pt-based drugs.
Aviva Levina, Debbie C. Crans, Peter A. Lay   +2 more
doaj   +1 more source

Effects of Active Participation and Education of Caregivers on Peripheral Intravenous Injections for Their Child [PDF]

, 2018
This study was to determine the effects of active participation and education of caregivers on the pain experienced by their hospitalized children, the anxiety of the caregivers, and the working efficiency of nurses when administering peripheral ...
Hwang, Eunmi, Kim, Yeon Sook, Kim, Phoebe (Yeon) S, Lee, Dongsuk   +3 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Physiologic parameters of the studied animals treated or not with EOC or ECO-CM intravenous injections.

, 2016
Physiologic parameters of the studied animals treated or not with EOC or ECO-CM intravenous injections.
Mariana A. B. Rosales (2142727), Jacqueline M. Lopes de Faria (2142730), José B. Lopes de Faria (2142724), Kerri Thai (252495), Diego A. Duarte (2142736), Alexandros Papadimitriou (2142733), Richard E. Gilbert (204424), Yanling Zhang (6561)   +7 more
core   +1 more source

Intravenous ibandronate injections in postmenopausal women with osteoporosis - One-year results from the dosing intravenous administration study [PDF]

, 2006
peer reviewedObjective. Although oral bisphosphonates are effective treatments for postmenopausal women with osteoporosis, oral dosing may be unsuitable for some patients.
Delmas, Pierre D., Civitelli, Roberto, Adami, Silvano, Strugala, Cezary, Recker, Robert R., Bolognese, Michael, Stakkestad, Jacob A., Sambrook, Philip, Reid, David M., Masanauskaite, Daiva, Felsenberg, Dieter, Christiansen, Claus, Ward, Penelope, Reginster, Jean-Yves, Drezner, Marc K., Hughes, Claire   +15 more
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Efficacy and safety of subcutaneous and intravenous rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in first-line diffuse large B-cell lymphoma: the randomized MabEase study

Haematologica, 2017
Intravenous rituximab plus chemotherapy is standard treatment for diffuse large B-cell lymphoma. A subcutaneous formulation of rituximab is expected to simplify and shorten drug preparation and administration, and to reduce treatment burden.
Pieternella Lugtenburg, Irit Avivi, Henriette Berenschot, Osman Ilhan, Jean Pierre Marolleau, Arnon Nagler, Antonio Rueda, Monica Tani, Mehmet Turgut, Stuart Osborne, Rodney Smith, Michael Pfreundschuh   +11 more
doaj   +1 more source

Toxicity Assessment of Mesoporous Silica Nanoparticles upon Intravenous Injection in Mice: Implications for Drug Delivery

Pharmaceutics, 2022
Nanoparticles are popular tools utilized to selectively deliver drugs and contrast agents for identification and treatment of disease. To determine the usefulness and translational potential of mesoporous silica nanoparticles (MSNs), further evaluations ...
William M. MacCuaig, Abhilash Samykutty, Jeremy Foote, Wenyi Luo, Alexander Filatenkov, Min Li, Courtney Houchen, William E. Grizzle, Lacey R. McNally   +8 more
doaj   +1 more source

Pharmacology of Intravenous Anesthetics

, 2022
Intravenous anesthetics are commonly used in modern anesthesia for induction and maintenance of general anesthesia and for sedation in various clinical settings (e.g., ICU, short procedures, pediatrics). This thesis gives an overview of the mechanism
Wang, Cong-Tian
core