Results 121 to 130 of about 84,735 (254)

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

De-implementing spinal injections in pursuit of value-based care: Rethinking pain relief. [PDF]

J Pain
Ballengee LA, Lentz TA, Goertz C, McStay F, Morken I, George SZ.   +5 more
europepmc   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Comparing Medicare Claims in Patients with Lumbar Discogenic Pain Managed Conservatively or with Intradiscal Nucleus Pulposus Allograft. [PDF]

J Pain Res
Girardi GE, Wilson DK, Patel RG, Yazdani S.   +3 more
europepmc   +1 more source

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

Advanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu, Yijie Hou, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Shuaiqi Li, Maohua Chen, Guichuan Xing, Dongbo Guo, Songnan Qu   +9 more
wiley   +1 more source

Abrupt Loss of Spinal Cord Stimulation After Trauma: A Case-Based Approach to Evaluation and Management. [PDF]

Orthop Rev (Pavia)
Hasoon J, Aner MM, Yazdi C, Robinson CL.
europepmc   +1 more source

Explainable AI‐Driven Optimization of Electrode Activation Reduces Power Consumption While Preserving Object Recognition in Retinal Prostheses

Advanced Intelligent Systems, EarlyView.
Explainable artificial intelligence (XAI) guides selective electrode activation in retinal prostheses by emphasizing visually informative regions. XAI‐assisted phosphene generation maintains object recognition performance while significantly reducing stimulation power.
Sein Kim, Hamin Shim, Maesoon Im
wiley   +1 more source

International Pain and Spine Intervention Society Emergency Protocols: Traumatic Spinal Cord Injury. [PDF]

Interv Pain Med
Klessinger S, DeFrancesch F, Schuster NM.   +2 more
europepmc   +1 more source

Design and Characterization of a Dual‐Mode Soft Robotic Flapping Propeller With Pneumatic Stiffness Modulation

Advanced Intelligent Systems, EarlyView.
A novel soft robotic propeller overcomes traditional efficiency‐flexibility tradeoffs via a hybrid pneumatic‐cable actuation strategy. This architecture enables active stiffness modulation with dual‐mode locomotion: tunable biomimetic swimming and earthworm‐inspired wriggling for confined spaces.
Jiazi Geng, Hua Shao, Yiyang Li, Lin Liang, Jinfeng Yang, Xianhong He, Fengran Xie   +6 more
wiley   +1 more source

Risk of Cervical Spine Complications in Individuals with Cervical Dystonia Treated with Botulinum Toxin Therapy. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Senthil S, Kumar S, Shukla AW.
europepmc   +1 more source