Neuronal differentiation and tissue engineering strategies for central neurous system injury repair
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia +9 more
wiley +1 more source
Factors associated with transforaminal epidural steroid injection efficacy and prognosis for symptomatic treatment of lumbar stenosis associated with degenerative scoliosis. [PDF]
MacNeil T +4 more
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Development and pilot testing of U1 Adaptor therapy targeting SOD1 expression for dogs with degenerative myelopathy. [PDF]
Olby NJ +9 more
europepmc +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Nonoperative Treatment of Adult Spinal Deformity: A Comprehensive Narrative Review. [PDF]
Zlatanos CG +4 more
europepmc +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
AAV2retro Enters Axons of Passage and Extensively Transduces Corticospinal Neurons After Injection into Spinal White Matter. [PDF]
Nakashima KT, Wang S, Castle MJ.
europepmc +1 more source
Force stimulation promotes nerve regeneration by restoring cellular energy
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang +10 more
wiley +1 more source
Lumbosacral Foraminal Injections in Dogs: Preliminary Assessment of an Ultrasound- and Fluoroscopy-Guided Technique in a Cadaveric Model. [PDF]
Medina-Serra R +4 more
europepmc +1 more source

