Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity [PDF]
Synaptic long-term potentiation (LTP) at spinal neurons directly communicating pain-specific inputs from the periphery to the brain has been proposed to serve as a trigger for pain hypersensitivity in pathological states.
Todd, A. J. +102 more
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Distribution of glycine/GABA neurons in the ventromedial medulla with descending spinal projections and evidence for an ascending glycine/GABA projection. [PDF]
The ventromedial medulla (VM), subdivided in a rostral (RVM) and a caudal (CVM) part, has a powerful influence on the spinal cord. In this study, we have identified the distribution of glycine and GABA containing neurons in the VM with projections to the
Mehdi Hossaini +3 more
doaj +1 more source
Introduction Abdominal spasms are involuntary contractions that can be caused by denervation due to spinal cord injury. We present a case that benefited from botulinum toxin injections.
KARADAĞ SAYGI, NAİME EVRİM +1 more
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Spine injections: the rationale for CT guidance [PDF]
Back pain is one of the most common medical problems and is associated with high socioeconomic costs. Imaging-guided spinal injections are a minimally invasive method to evaluate where the back pain is originating from, and to treat patients with ...
Reto Sutter +5 more
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Two Cases of Iatrogenic Lumbar Foraminal Disc Herniations
Study Design. A case report. Objective. We report two cases of iatrogenic deterioration of lumbar foraminal disc herniations following lumbar disc injections. Summary of Background Data. Complications associated with discography were reported.
Ryota Taniguchi +4 more
doaj +1 more source
Facet joint injections for management of low back pain: a clinically focused review [PDF]
Lumbar facet joints have been implicated in chronic low back pain in up to 45% of patients with low back pain (LBP). Facet joint pain diagnosis and management are always challenging for pain physicians.
Hyung-Sun Won +2 more
doaj +1 more source
Stem Cell Clinical Trials in Spinal Cord Injury: A Brief Review of Studies in the United States
Background: Although many therapeutic approaches have been attempted to treat spinal cord injury, cellular transplantation offers the greatest promise in reconstituting the architecture of the damaged cord.
Andrew Platt +2 more
doaj +1 more source
Background Spinal epidural lipomatosis is an uncommon source of neurogenic claudication. We present two cases of spinal epidural lipomatosis as it relates to diagnosis, management, and a possible association with common medical intervention.
Keith M. Silcox +4 more
doaj +1 more source
Comparative Clinical Effectiveness of Management Strategies for Sciatica: Systematic Review and Network Meta-Analyses [PDF]
Background There are numerous treatment approaches for sciatica. Previous systematic reviews have not compared all these strategies together. Purpose To compare the clinical effectiveness of different treatment strategies for sciatica simultaneously.
Rickard, I +47 more
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Spinal Injections: A Narrative Review from a Surgeon’s Perspective
Spinal pain is one of most frequent complaints of the general population, which can cause decreased activities of daily living and absence from work. Among numerous therapeutic methods, spinal injection is one of the most effective treatments for spinal ...
Yoo Jin Choo +2 more
core +1 more source

