Upper arm administration is associated with higher injection site pain with romosozumab: a randomized controlled trial and a self-controlled study. [PDF]
Tani S +9 more
europepmc +1 more source
Comparison of intratesticular lidocaine, sacrococcygeal epidural lidocaine and intravenous methadone in cats undergoing castration: a prospective, randomized, investigator-blind clinical trial [PDF]
Adami, C +3 more
core +2 more sources
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez +17 more
wiley +1 more source
Development of Artificial Sebaceous Gland‐Integrated In Vitro Human Skin Model
Uniform 3D artificial sebaceous gland spheroids, termed SebaSpheres, are generated at high throughput using a microfluidic platform and structurally integrated into a collagen‐based skin construct containing fibroblasts and keratinocytes. This work presents a modular and scalable fabrication and integration strategy for incorporating sebaceous gland ...
Daeun Ryu +7 more
wiley +1 more source
Bilateral rectus sheath hematoma following enoxaparin administration in a patient with extensive lower limb DVT: a rare complication. [PDF]
Mehrotra R +3 more
europepmc +1 more source
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
Limited willingness to switch from intravenous to subcutaneous treatment in paediatric inflammatory bowel disease. [PDF]
Eindor-Abarbanel A +11 more
europepmc +1 more source
Vat Polymerization 3D Printing for Controlled Drug Release Applications
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari +2 more
wiley +1 more source
Reducing treatment burden in HER2+ breast cancer: Evaluating subcutaneous injection methods for pertuzumab/trastuzumab combination therapy. [PDF]
Zheng R +6 more
europepmc +1 more source
Engineered Optical Fibers for Deep‐Tissue Applications
This review establishes a foundational framework for designing optical fibers for deep‐tissue medicine. It systematically links material innovations like polymers and hydrogels with structural paradigms to enable state‐of‐the‐art diagnostics, including endoscopy and biosensing, and targeted therapeutics, guiding future clinical translation.
Yuzhen Li +16 more
wiley +1 more source

