Results 41 to 50 of about 139,649 (304)

Procedural pain and patient-reported side effects with weekly injections of subcutaneous Methotrexate in children with rheumatic disorders [PDF]

open access: yes, 2015
Background Despite the widespread use of subcutaneous methotrexate in treating pediatric rheumatic disorders, the amount of pain associated with the injections has not been quantified.
Ciaran Duffy   +13 more
core   +4 more sources

The Subcutaneous Injection of Organophosphate: A Case Report

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2021
Organophosphate (OP) poisoning is prevalent in developing countries. Toxicity occurs by voluntary injection, inhalation, and absorption. Self-injection is rare.
Shafeajafar Zoofaghari   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2014
Background Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is more than 0.02 cc for dermal hydration.
Jongseo Kim
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Scintigraphic investigations of the superficial lymphatic system: quantitative differences between intradermal and subcutaneous injections. [PDF]

open access: yes, 2009
Both subcutaneous and intradermal injections are used for the scintigraphic investigations of the superficial lymphatic system. The qualitative differences between these types of injections are well known.
Leduc, Albert   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Lipomembranous panniculitis after subcutaneous medroxyprogesterone acetate injections used for buttocks augmentation in Africa [PDF]

open access: yes, 2021
© 2021 the International Society of DermatologyWe describe a series of four African women with lipomembranous panniculitis after subcutaneous injections of depot medroxyprogesterone acetate (DMPA), a synthetic progestin commonly used as a contraceptive ...
Soares-de-Almeida, Luís   +4 more
core   +1 more source

Visualization of subcutaneous insulin injections by x-ray computed tomography [PDF]

open access: yes, 2012
We report how the three-dimensional structure of subcutaneous injections of soluble insulin can be visualized by x-ray computed tomography using an iodine based contrast agent.
Velroyen, A.   +13 more
core   +3 more sources

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