Results 31 to 40 of about 4,554,937 (345)

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng   +12 more
doaj   +1 more source

SUZ12 Loss Amplifies the Ras/ERK Pathway by Activating Adenylate Cyclase 1 in NF1-Associated Neurofibromas

Frontiers in Oncology, 2021
Patients with germline neurofibromatosis type 1 (NF1) microdeletions frequently exhibit hereditary syndromes such as cardiovascular anomalies and have an increased risk of malignant peripheral nerve sheath tumors (MPNSTs).
Weijie Li, Chenhao Hu, Xingnan Zhang, Binbin Wang, Zhen Li, Miao Ling, Shengqiao Sun, Chao Guo, Dezhi Li, Song Liu, Song Liu   +10 more
doaj   +1 more source

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

BMC Neurology, 2021
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug, Tamara Spingler, Cornelia Hensel, Stefan Fichtner, Tiziana Daniel, Laura Heutehaus, Michel Wensing, Rüdiger Rupp, Norbert Weidner   +8 more
doaj   +1 more source

Circulating Mitochondrial DAMPs Cause Inflammatory Responses to Injury

Nature, 2009
Injury causes a systemic inflammatory response syndrome (SIRS) that is clinically much like sepsis. Microbial pathogen-associated molecular patterns (PAMPs) activate innate immunocytes through pattern recognition receptors. Similarly, cellular injury can
Qin Zhang, M. Raoof, Yu Chen, Y. Sumi, T. Sursal, W. Junger, K. Brohi, K. Itagaki, C. Hauser   +8 more
semanticscholar   +1 more source

Preserved gait kinematics during controlled body unloading

Journal of NeuroEngineering and Rehabilitation, 2017
Background Body weight supported locomotor training was shown to improve walking function in neurological patients and is often performed on a treadmill.
L. Awai, M. Franz, C. S. Easthope, H. Vallery, A. Curt, M. Bolliger   +5 more
doaj   +1 more source

Barriers to recruitment, retention and intervention delivery in a randomized trial among patients with firearm injuries

Injury Epidemiology, 2021
Background We discuss barriers to recruitment, retention, and intervention delivery in a randomized controlled trial (RCT) of patients presenting with firearm injuries to a Level 1 trauma center.
Anthony S. Floyd, Vivian H. Lyons, Lauren K. Whiteside, Kevin P. Haggerty, Frederick P. Rivara, Ali Rowhani-Rahbar   +5 more
doaj   +1 more source

Incidence and outcomes of acute lung injury.

New England Journal of Medicine, 2005
BACKGROUND Acute lung injury is a critical illness syndrome consisting of acute hypoxemic respiratory failure with bilateral pulmonary infiltrates that are not attributed to left atrial hypertension.
G. Rubenfeld, E. Caldwell, E. Peabody, J. Weaver, Diane P. Martin, M. Neff, E. Stern, L. Hudson   +7 more
semanticscholar   +1 more source

Robotic body weight support enables safe stair negotiation in compliance with basic locomotor principles

Journal of NeuroEngineering and Rehabilitation, 2019
Background After a neurological injury, mobility focused rehabilitation programs intensively train walking on treadmills or overground. However, after discharge, quite a few patients are not able to independently negotiate stairs, a real-world task with ...
M. Bannwart, E. Rohland, C. A. Easthope, G. Rauter, M. Bolliger   +4 more
doaj   +1 more source

A bibliometric analysis of the published road traffic injuries research in India, post-1990

Health Research Policy and Systems, 2018
Background Globally, road traffic injuries are the leading cause of death among those aged 15–29 years. However, road traffic injury research has not received adequate attention from the scientific community in low- and middle-income countries, including
Neeraj Sharma, Mohan Bairwa, B. Gowthamghosh, S. D. Gupta, D. K. Mangal   +4 more
doaj   +1 more source

Reactive oxygen species in inflammation and tissue injury.

Antioxidants and Redox Signaling, 2014
Reactive oxygen species (ROS) are key signaling molecules that play an important role in the progression of inflammatory disorders. An enhanced ROS generation by polymorphonuclear neutrophils (PMNs) at the site of inflammation causes endothelial ...
M. Mittal, M. Siddiqui, Khiem Tran, S. Reddy, A. Malik   +4 more
semanticscholar   +1 more source