Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
A discussion of statistical criteria for assessing awareness with SMR BCI after brain injury [PDF]
Idorenyin A. Amaunam +5 more
openalex +1 more source
Impact of Baseline Magnetic Resonance Imaging on Neurologic, Functional, and Safety Outcomes in Patients With Acute Traumatic Spinal Cord Injury [PDF]
Study Design: Systematic review. Objective: To perform a systematic review to evaluate the utility of magnetic resonance imaging (MRI) in patients with acute spinal cord injury (SCI).
Aarabi, Bizhan +10 more
core +2 more sources
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Dummy and Injury Criteria for Aircraft Crashworthiness [PDF]
<div class="htmlview paragraph">Since 1988, newly type certificated aircraft are required to comply with stringent crashworthiness requirements. Central to these more stringent requirements is a dynamic test that assesses the potential for injury for someone exposed to similar conditions. In this paper the techniques and reference values used for
openaire +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Profil Pasien Luka Bakar Berat Yang Meninggal Di RSUD Arifin Achmad Provinsi Riau Periode Januari 2011 - Desember 2013 [PDF]
Burn injury is one of trauma with high number of morbidity and mortality rate that needs comprehensive treatment from acute phase, subacute phase and chronic phase.
Giovany, L. G. (Lisa) +2 more
core
Classification of lower extremity movement patterns based on visual assessment: reliability and correlation with 2-dimensional video analysis [PDF]
CONTEXT: Abnormal movement patterns have been implicated in lower extremity injury. Reliable, valid, and easily implemented assessment methods are needed to examine existing musculoskeletal disorders and investigate predictive factors for lower extremity
Graci, Valentina +5 more
core +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source

