A method for defining tissue injury criteria reveals that ligament deformation thresholds are multimodal. [PDF]
Acta Biomater, 2023 Luetkemeyer CM, Neu CP, Calve S.
europepmc +1 more source
Rett Syndrome: Revised diagnostic criteria and nomenclature [PDF]
, 2010 Objective: Rett syndrome (RTT) is a severe neurodevelopmental disease that affects approximately 1 in 10,000 live female births and is often caused by mutations in Methyl-CpG-binding protein 2 (MECP2). Despite distinct clinical features, the accumulation
Leonard, Helen +44 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Assessment of the sensitivity of thoracic injury criteria to subject-specific characteristics using human body models. [PDF]
Front Bioeng Biotechnol, 2023 Piqueras A +3 more
europepmc +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Evaluation of mechanism of injury criteria for field triage of occupants involved in motor vehicle collisions. [PDF]
Traffic Inj Prev, 2022 Hartka T, Glass G, Chernyavskiy P.
europepmc +1 more source
The impact of intimacy and disability on the perception toward rehabilitation processes of a person with traumatic injury [PDF]
, 2003 Plan BThe purpose of this descriptive research study was to investigate any possible interactions between the person with a traumatic injury and their perceptions of rehabilitation processes dependent on their spousal/domestic partner relationship status
Desler, Sandra
core
RIFLE Criteria in Critically Ill Neonates with Acute Kidney Injury
, 2015 Introduction: Diagnosis of neonatal acute kidney injury (AKI) is a difficult dilemma and there is no consensus in this regard. Based on RIFLE criteria the definition of ARF is changed lately in adult and pediatric groups.
Afjeii, Abolfazl +4 more
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Do sleep difficulties exacerbate deficits in sustained attention following traumatic brain injury? [PDF]
, 2010 Sustained attention has been shown to be vulnerable following traumatic brain injury (TBI). Sleep restriction and disturbances have been shown to negatively affect sustained attention. Sleep disorders are common but under-diagnosed after TBI.
Espie, C.A. +2 more
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