Results 71 to 80 of about 47,020 (246)

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

Deep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh, Tonni Agustiono Kurniawan, Christia Meidiana, Abdelkader Anouzla, Faissal Aziz, Imran Ali, Joan Cecilia C. Casila, M. Imran Khan, Dongdong Zhang, Meihui Jiang, Mohd Hafiz Dzarfan Othman, Md Munir Hayet Khan, Kasun Kumara Dissanayake   +12 more
wiley   +1 more source

The role and mechanism of transcription factor KLF4 in regulating mitochondrial damage and apoptosis by activating chondrocyte autophagy in osteoarthritis

Scientific Reports
Objective To explore the role and mechanism of transcription factor KLF4 in regulating mitochondrial damage and apoptosis by activating chondrocyte autophagy.
Wenguang Feng, Haibin Wang, Guoliang Zhang, Wang Gao, Hongcang LI, Haibo Liu, Yanhong Sun   +6 more
doaj   +1 more source

Norcantharidin inhibits TOP2A expression via H3K27me3 mediated epigenetic regulation to alleviate the progression of hepatocellular carcinoma

Frontiers in Pharmacology
BackgroundNorcantharidin (NCTD), a bioactive compound derived from traditional Chinese medicine, has demonstrated promising anticancer activity against multiple malignancies, particularly hepatocellular carcinoma (HCC). However, its epigenetic regulatory
Ruibing Wu, Hengye Yuan, Yuehua Wang, Xianggang Gou, Wanhua Hou, Zhongzheng Zhou, Xinran Wang, Xiuling Deng, Changshan Wang, Haisheng Wang, Jia Yan, Jia Yan   +11 more
doaj   +1 more source

Fracture evolution of a thick soft protection layer and the water inrush mechanism in overburden under longwall mining

Deep Underground Science and Engineering, EarlyView.
Through shear–tensile creep tests and viscoelastic modeling, the fracture evolution of thick soft protective layers is clarified. Results show thickness‐dependent rheological failure modes that govern four types of roof water inrush, providing a mechanism‐based framework for hazard prediction and control. Abstract In the Jurassic coal‐bearing strata of
Mengnan Liu, Wei Qiao, Xianggang Cheng, Xiangsheng Meng, Peichao Feng   +4 more
wiley   +1 more source

Mechanism and disaster control new technology of strong ground pressure manifestation in ultra‐large mining face

Deep Underground Science and Engineering, EarlyView.
In response to the problem of strong mining pressure manifestation along the goaf roadway in a thick coal seam mining area, this study uses a new type of combined blasting roof cutting technology to effectively control the manifestation and deformation of mining pressure along the goaf roadway.
Xiaoding Xu, Manchao He, Jun Yang, Yubing Gao, Qiang Fu, Qing Ma, Yajun Wang   +6 more
wiley   +1 more source

Engineering the Lattice and Electronic Configurations of N‐Rich‐CoMoCN by Mo Doping and N Enrichment for Enhanced Water Splitting

EcoEnergy, EarlyView.
This study design Mo‐doped and N‐rich‐CoMoCN bimetal for bi‐functionally efficient overall water splitting catalysts by constructing an active site and engineering the interfacial Co6Mo6C2/Co heterojunction in a N‐doped porous carbon matrix and study on the performance of catalyst for electrocatalytic.
Huimin Yang, Yue Xiao, Zhuo Wang, Mingfang Zhang, Haimei Xu, Yunzhao Fan, Chao Feng, Qingcheng Hu, Chunhua Yuan, Yang Fu, Lingfeng Zhu, Songbo Li, Tianyi Ma   +12 more
wiley   +1 more source

Locking Fe Single Atoms Into the Lattices of Mesoporous TiO2 Promotes Nitrogen Reduction

EcoEnergy, EarlyView.
S‐coordinated Fe single‐atom catalysts on mesoporous TiO2 have been constructed by a universal lattice‐confined strategy. This catalyst shows a unique nanoconfinement effect for mass transfer and maximizes the active sites to mimic nitrogenase for ambient electrocatalytic N2 reduction reaction.
Danli Liang, Ruicong Wang, Yujuan Zhao, Zaiwang Zhao   +3 more
wiley   +1 more source

Tuning S Doping in Porous Carbon for Enhanced Initial Coulombic Efficiency and Rate Performance for Sodium/Potassium‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Low‐temperature carbonization and sulfur doping increase defect density and tailor surface area, enabling the formation of a thinner, more stable SEI, enhancing rate performance and the ICE. The S/C composite delivers an ICE of 83.1% and 480 mAh g−1 at 0.1 A g−1, retaining 232.6 mAh g−1 at 5 A g−1 for SIBs and achieves a considerable capacity of 439.2 ...
Jiahao Zhao, Lankun Shi, Mengting Jia, Yu Gao, Zhongmin Lang, Boyu Sun, Jinlong Cui, Shaohui Li   +7 more
wiley   +1 more source

Sustained‐Release Ulcer‐Protective Microarray Patch With Dihydrocapsaicin for Diabetic Wound Regeneration

Exploration, EarlyView.
Schematic illustration of the effect of microneedles incorporating cerium‐based MOF loading dihydrocapsaicin (MN‐MOF@DHC) to scavenge reactive oxygen species (ROS) generation, beanti‐inflammatory, inhibit the apoptosis of endothelial cells (ECs), promote angiogenesis, and accelerate diabetic wound healing. ABSTRACT Diabetic foot ulcers (DFUs) present a
Yuxu Wu, Kan Jiang, Xiao Wen, Chihao Jin, Kai Zhang, Jiakai Zhang, Jiale Jin, Jiaqian Wang, Huiyu Hu, Zonghan Xu, Xianzhu Zhang, Yihe Hu   +11 more
wiley   +1 more source

Construction of the pCHD-21X19EpCAM-CAR lentiviral vector and generation of CAR-engineered natural killer cells from human PBMCs

European Journal of Medical Research
Background Colorectal cancer (CRC) is a highly prevalent malignancy of the digestive system worldwide, necessitating the development of safe and effective therapeutic strategies.
Bingping Wang, Jinkai Duan, Hulin Ma, Meng Ren, Liangquan Chen, Rina Su, Hao Zhang, Shuang Zhang, Yanwei Gao   +8 more
doaj   +1 more source